CDC42BPG

Serine/threonine-protein kinase MRCK gamma · Q6DT37 · CDC42BPG on Sugi Atlas →

511 patent compounds predicted against CDC42BPG, 477 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL4135600 SCHEMBL4135600 0.78 2/20
SCHEMBL2650684 SCHEMBL2650684 0.75 2/20
SCHEMBL6465326 SCHEMBL6465326 0.74 2/20
SCHEMBL4553131 SCHEMBL4553131 0.70 2/20
SCHEMBL7231228 SCHEMBL7231228 0.70 2/20
SCHEMBL2648503 SCHEMBL2648503 0.70 2/20
SCHEMBL2649542 SCHEMBL2649542 0.70 2/20
SCHEMBL4551864 SCHEMBL4551864 0.70 2/20
SCHEMBL7249555 SCHEMBL7249555 0.70 2/20
SCHEMBL19857269 SCHEMBL19857269 0.70 2/20
SCHEMBL21169981 SCHEMBL21169981 0.70 2/20
SCHEMBL2649978 SCHEMBL2649978 0.66 2/20
SCHEMBL19868852 SCHEMBL19868852 0.66 2/20
SCHEMBL2650680 SCHEMBL2650680 0.66 2/20
SCHEMBL13497841 SCHEMBL13497841 0.65 2/20
SCHEMBL19857273 SCHEMBL19857273 0.65 2/20
SCHEMBL4553479 SCHEMBL4553479 0.63 2/20
SCHEMBL8486792 SCHEMBL8486792 0.62 2/20
SCHEMBL4569577 SCHEMBL4569577 0.62 2/20
SCHEMBL9196324 SCHEMBL9196324 0.61 2/20

Clinical trials — most relevant to CDC42BPG by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Eicosapentaenoic Acid Cerebral Vasospasm Therapy Study PHASE4COMPLETED
Short-Term Metformin Use in Young, Healthy Adults: Impacts on Exercise Capacity PHASE4COMPLETED
The G Protein-Coupled Receptor Kinase Type 2 Inhibitor Paroxetine as Adjunctive Therapy to Improve Insulin Sensitivity in Patients With Type 2 Diabetes Mellitus PHASE3UNKNOWN
Autologous Cytokine Induced Killer Cells (CIK) for Chronic Myeloid Leukemia (CML) Patients on Standard Drug Therapy PHASE2COMPLETED
PKC412 and 5-Azacytidine PHASE1/PHASE2COMPLETED
Study of Sorafenib and Docetaxel in Metastatic Prostate Cancer PHASE2COMPLETED
Safety and Impact of Dasatinib on Viral Persistence and Inflammation in People With HIV Under Antiretroviral Treatment PHASE2COMPLETED
Cabozantinib-S-Malate in Treating Patients With Refractory Thyroid Cancer PHASE2COMPLETED
A Phase II Study of EVEROLIMUS in Patients With Primary or Relapsed Chondrosarcomas PHASE2SUSPENDED
Phase II Dasatinib Study in Advanced Breast Cancer PHASE2COMPLETED
FAK Inhibitor in Patients With Advanced Solid Tumors PHASE1NOT_YET_RECRUITING
Temsirolimus and Sorafenib in Advanced Hepatocellular Carcinoma PHASE1COMPLETED
Interleukin-2 Treatment for Wiskott-Aldrich Syndrome PHASE1COMPLETED
Safety and Efficacy of the Fully Humanized Anti - VEGF Monoclonal Antibody LYN00101 PHASE1WITHDRAWN
Pre-Surgical Trial of the Combination of Metformin and Atorvastatin in Newly Diagnosed Operable Breast Cancer EARLY_PHASE1COMPLETED
Evaluation of the Changes in Matrix Metalloproteinase-9 Levels With Salvadora Persica (Miswak) in Periodontal Fibroblasts and Gingival Crevicular Fluid in Patients With Periodontitis EARLY_PHASE1NOT_YET_RECRUITING
ADRB3, ROCK2 and GEF Levels in Overactive Bladder Patients nanCOMPLETED
Study of the Pathophysiological Mechanisms Involved in Bleeding Events nanCOMPLETED
C-X-C Chemokine Receptor 4 in Chronic Lymphocytic Leukemia nanUNKNOWN
Identification of Novel Targetable Kinases in SR-a GvHD nanCOMPLETED
Role of Chemokine and Chemokine Receptor in Psoriasis nanWITHDRAWN
Pathological and Nuclear Medicine Factors for Prognosis in Lung Carcinoma nanCOMPLETED
p-AKT Expression on Clinical Outcomes in Malignant Lymphoma nanCOMPLETED
Pulsed Electro Magnetic Fields (PEMF) in Depression nanCOMPLETED
Regulation of Lymphocyte Anti-tumor Response in Metastatic Patients Treated With the mTOR Inhibitor Everolimus nanCOMPLETED
Novel Biomarkers in Inflammatory Bowel Disease nanCOMPLETED
Abnormalities in the Effects of Insulin and Exercise on Glucose- and Lipid Metabolism in Obesity and Type 2 Diabetes nanCOMPLETED
Immune Cell Response to Stimuli nanRECRUITING
Identification of an Asthma Susceptibility Gene on 3P nanCOMPLETED
Investigation of Methylation of EGFR in the Response of the Cetuximab in Metastatic Colorectal Cancer Patients nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a CDC42BPG binder may also engage these)

ProteinNameSimilarity
Q80UW5 1.000 Q80UW5 →
Q80XI6 0.992 Q80XI6 →
Q8C2K1 0.991 Q8C2K1 →
P58660 0.991 P58660 →
Q9JIR0 0.991 Q9JIR0 →
Q9BWT7 0.989 Q9BWT7 →
Q66HA1 0.989 Q66HA1 →
P97680 0.989 P97680 →
Q921Q7 0.989 Q921Q7 →
P54265 0.989 P54265 →
Q99ML2 0.988 Q99ML2 →
Q9BXL6 0.988 Q9BXL6 →
Q8WWN8 0.987 Q8WWN8 →
TNK1 Non-receptor tyrosine-protein kinase TNK1 0.987 landscape →
Q99KF0 0.987 Q99KF0 →
Q96P48 0.987 Q96P48 →
RIN1 Ras and Rab interactor 1 (Ras inhibitor JC99) 0.987 landscape →
Q9H4E7 0.987 Q9H4E7 →
Q6ZVH7 0.987 Q6ZVH7 →
B3EX63 0.987 B3EX63 →
Q8BXP5 0.986 Q8BXP5 →
A4FUG8 0.986 A4FUG8 →
Q9BRR9 0.986 Q9BRR9 →
Q5TJE5 0.986 Q5TJE5 →
O75064 0.986 O75064 →
D2H0G5 0.986 D2H0G5 →
Q96HA7 0.986 Q96HA7 →
Q924T7 0.986 Q924T7 →
Q9BYX2 0.986 Q9BYX2 →
Q4LDD4 0.986 Q4LDD4 →