Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 9/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.40 |
| ▸ | HSD17B3 | P37058 | 2/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | REV1 | Q9UBZ9 | 1/20 | 0.39 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21765905 | 0.89 | MAPT (0.45) | ESR1NPC1RAB9AALDH1A1L3MBTL1 | |
| SCHEMBL6301951 | 0.87 | ESR1 (0.44) | ESR1NPC1RAB9AALDH1A1L3MBTL1 | |
| SCHEMBL7182118 | 0.84 | ESR1 (0.47) | ESR1ALDH1A1ESR2HSD17B3MAPT | |
| SCHEMBL1830052 | 0.84 | ESR1 (0.47) | ESR1ALDH1A1ESR2HSD17B3MAPT | |
| SCHEMBL10192055 | 0.81 | MAPT (0.59) | ALDH1A1L3MBTL1MAPTLMNATDP1 | |
| SCHEMBL14234293 | 0.79 | FFAR1 (0.45) | L3MBTL1APPREV1MAPTLMNA | |
| SCHEMBL9467431 | 0.79 | APP (0.39) | NPC1RAB9AAPPREV1MAPT | |
| SCHEMBL14234071 | 0.79 | ALDH1A1 (0.50) | ALDH1A1MAPTPGRCYP3A4ALOX15 | |
| SCHEMBL11356266 | 0.78 | NPC1 (0.49) | ESR1NPC1RAB9AALDH1A1L3MBTL1 | |
| SCHEMBL13762630 | 0.78 | CA12 (0.50) | ESR1ALDH1A1REV1MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6921740-B1 | Electron-receiving compound and thermal recording material | MITSUBISHI PAPER MIILS LTD. (JP) | 2005-07-26 | — | — | US | disclosed |
| US-6579829-B2 | Aromatic sulfonamide compound | MITSUI CHEMICALS, INC. (JP) | 2003-06-17 | — | — | US | disclosed |
| EP-1138517-A2 | Developer composition and heat sensitive recording material | Mitsui Chemicals, Inc. (JP) | 2001-10-04 | — | — | EP | disclosed |