Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.31 |
| ▸ | KDM4A | O75164 | 1/20 | 0.31 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.31 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29065774 | 0.87 | CES1 (0.35) | LMNAPTPN1CA1BLMKDM1A | |
| SCHEMBL6626453 | 0.87 | LMNA (0.35) | LMNAPTPN1CA1BLMKDM1A | |
| SCHEMBL926657 | 0.82 | CA1 (0.43) | LMNACA1 | |
| SCHEMBL16244845 | 0.79 | FFAR4 (0.42) | LMNA | |
| SCHEMBL988399 | 0.76 | PTPN1 (0.41) | LMNAPTPN1CA1BLMKDM1A | |
| SCHEMBL1626506 | 0.74 | LMNA (0.48) | LMNAPTPN1CA1BLMKDM4C | |
| SCHEMBL11594555 | 0.74 | LMNA (0.48) | LMNAPTPN1CA1BLMKDM4C | |
| SCHEMBL128911 | 0.74 | TDP1 (0.43) | LMNAPTPN1CA1BLMKDM1A | |
| SCHEMBL11692425 | 0.74 | LMNA (0.36) | LMNAPTPN1CA1BLMKDM1A | |
| SCHEMBL8579213 | 0.72 | CA1 (0.40) | CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6849743-B2 | Synthesis of clasto-lactacystin β-lactone and analogs thereof | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2005-02-01 | — | — | US | disclosed |
| US-5436231-A | HYPERTENSIVE AGENTS | SANKYO COMPANY, LIMITED (JP) | 1995-07-25 | — | — | US | disclosed |