Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP6V1B1 | P15313 | 5/20 | 0.70 |
| ▸ | ATP6AP1 | Q15904 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6295637 | 1.00 | ATP6V1B1 (0.70) | ATP6V1B1ATP6AP1KDM4EALDH1A1HPGD | |
| SCHEMBL6295634 | 1.00 | ATP6V1B1 (0.70) | ATP6V1B1ATP6AP1KDM4EALDH1A1HPGD | |
| SCHEMBL6292583 | 0.85 | ATP6V1B1 (0.93) | ATP6V1B1ATP6AP1 | |
| SCHEMBL6295583 | 0.83 | ATP6V1B1 (1.00) | ATP6V1B1ATP6AP1GAATSHRHSD17B10 | |
| SCHEMBL6295582 | 0.83 | ATP6V1B1 (1.00) | ATP6V1B1ATP6AP1GAATSHRHSD17B10 | |
| SCHEMBL6291701 | 0.81 | ATP6V1B1 (0.81) | ATP6V1B1ATP6AP1 | |
| SCHEMBL6291700 | 0.81 | ATP6V1B1 (0.81) | ATP6V1B1ATP6AP1 | |
| SCHEMBL6291696 | 0.81 | ATP6V1B1 (0.81) | ATP6V1B1ATP6AP1 | |
| SCHEMBL6374814 | 0.79 | ATP6V1B1 (0.74) | ATP6V1B1ATP6AP1 | |
| SCHEMBL6295623 | 0.79 | ATP6V1B1 (0.82) | ATP6V1B1ATP6AP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6903117-B2 | Indole derivatives for the treatment of osteoporosis | NIKEM RESEARCH S.R.L. (IT) | 2005-06-07 | — | — | US | disclosed |