Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 4/20 | 0.72 |
| ▸ | HSP90AA1 | P07900 | 7/20 | 0.61 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.61 |
| ▸ | IDO1 | P14902 | 1/20 | 0.61 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.61 |
| ▸ | MMP14 | P50281 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | METAP2 | P50579 | 2/20 | 0.52 |
| ▸ | METAP1 | P53582 | 2/20 | 0.52 |
| ▸ | BRD4 | O60885 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | APAF1 | O14727 | 1/20 | 0.50 |
| ▸ | TDP2 | O95551 | 1/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31434767 | 0.84 | HSP90AA1 (0.61) | NR4A2HSP90AA1HSP90AB1IDO1PSMB5 | |
| SCHEMBL2423195 | 0.84 | HSP90AA1 (0.61) | NR4A2HSP90AA1HSP90AB1IDO1PSMB5 | |
| SCHEMBL10009591 | 0.84 | NR4A2 (1.00) | NR4A2HSP90AA1HSP90AB1IDO1PSMB5 | |
| SCHEMBL196536 | 0.83 | KDM4E (0.70) | NR4A2HSP90AA1MMP14MAPTLMNA | |
| SCHEMBL7455899 | 0.83 | HSP90AA1 (0.70) | NR4A2HSP90AA1HSP90AB1IDO1PSMB5 | |
| SCHEMBL29661959 | 0.83 | HSP90AA1 (0.70) | NR4A2HSP90AA1HSP90AB1IDO1PSMB5 | |
| SCHEMBL18980424 | 0.76 | KMT2A (0.59) | NR4A2HSP90AA1MMP14MAPTLMNA | |
| SCHEMBL29777332 | 0.76 | KMT2A (0.59) | NR4A2HSP90AA1MMP14MAPTLMNA | |
| SCHEMBL3559305 | 0.76 | KDM4E (0.61) | NR4A2HSP90AA1IDO1MMP14MAPT | |
| SCHEMBL9185003 | 0.76 | KDM4E (0.72) | NR4A2HSP90AA1HSP90AB1IDO1PSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260062412-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND HAVING MYT1 INHIBITORY ACTIVITY | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2026-03-05 | — | — | US | disclosed |
| EP-4647424-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND HAVING MYT1 INHIBITORY ACTIVITY | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2025-11-12 | — | — | EP | disclosed |
| WO-2024181437-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND HAVING MYT1 INHIBITORY ACTIVITY | 中外製薬株式会社 | 2024-09-06 | — | — | WO | disclosed |
| US-6875764-B1 | Urea and thiourea compounds useful for treatment of coccidiosis | NEW PHARMA RESEARCH SWEDEN AB (SE) | 2005-04-05 | — | — | US | disclosed |
| EP-1224165-A1 | NOVEL COMPOUNDS | New Pharma Research Sweden AB (SE) | 2002-07-24 | — | — | EP | disclosed |
| WO-2001030749-A1 | NOVEL COMPOUNDS | NEW PHARMA RESEARCH SWEDEN AB (SE) | 2001-05-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260062412-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND HAVING MYT1 INHIBITORY ACTIVITY | MYT1, NTMT1, MYL6 | NR4A2 2643/4885HSP90AA1 3636/4885HSP90AB1 3497/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.