Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP6V1B1 | P15313 | 4/20 | 0.80 |
| ▸ | ATP6AP1 | Q15904 | 1/20 | 0.52 |
| ▸ | DRD2 | P14416 | 5/20 | 0.47 |
| ▸ | DRD3 | P35462 | 4/20 | 0.47 |
| ▸ | DRD4 | P21917 | 4/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6296250 | 1.00 | ATP6V1B1 (0.80) | ATP6V1B1ATP6AP1DRD2DRD3DRD4 | |
| SCHEMBL6296252 | 1.00 | ATP6V1B1 (0.80) | ATP6V1B1ATP6AP1DRD2DRD3DRD4 | |
| SCHEMBL6291920 | 0.94 | ATP6V1B1 (0.76) | ATP6V1B1DRD2DRD3DRD4ADRA1A | |
| SCHEMBL6291918 | 0.94 | ATP6V1B1 (0.76) | ATP6V1B1DRD2DRD3DRD4ADRA1A | |
| SCHEMBL6291919 | 0.94 | ATP6V1B1 (0.76) | ATP6V1B1DRD2DRD3DRD4ADRA1A | |
| SCHEMBL6363567 | 0.92 | ATP6V1B1 (0.80) | ATP6V1B1ATP6AP1DRD2DRD3DRD4 | |
| SCHEMBL6363568 | 0.92 | ATP6V1B1 (0.80) | ATP6V1B1ATP6AP1DRD2DRD3DRD4 | |
| SCHEMBL6291608 | 0.89 | ATP6V1B1 (0.83) | ATP6V1B1ATP6AP1DRD2DRD3DRD4 | |
| SCHEMBL6291607 | 0.89 | ATP6V1B1 (0.83) | ATP6V1B1ATP6AP1DRD2DRD3DRD4 | |
| SCHEMBL6291602 | 0.89 | ATP6V1B1 (0.83) | ATP6V1B1ATP6AP1DRD2DRD3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6903117-B2 | Indole derivatives for the treatment of osteoporosis | NIKEM RESEARCH S.R.L. (IT) | 2005-06-07 | — | — | US | disclosed |