Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP6V1B1 | P15313 | 5/20 | 0.76 |
| ▸ | ATP6AP1 | Q15904 | 1/20 | 0.57 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.34 |
| ▸ | GMNN | O75496 | 1/20 | 0.34 |
| ▸ | HTR3B | O95264 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.34 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6292859 | 1.00 | ATP6V1B1 (0.76) | ATP6V1B1ATP6AP1HTR3EGMNNHTR3B | |
| SCHEMBL6295583 | 0.86 | ATP6V1B1 (1.00) | ATP6V1B1ATP6AP1HTR3EGMNNHTR3B | |
| SCHEMBL6295582 | 0.86 | ATP6V1B1 (1.00) | ATP6V1B1ATP6AP1HTR3EGMNNHTR3B | |
| SCHEMBL6292583 | 0.83 | ATP6V1B1 (0.93) | ATP6V1B1ATP6AP1HTR3A | |
| SCHEMBL6295623 | 0.79 | ATP6V1B1 (0.82) | ATP6V1B1ATP6AP1TSHR | |
| SCHEMBL6291700 | 0.78 | ATP6V1B1 (0.81) | ATP6V1B1ATP6AP1 | |
| SCHEMBL6291701 | 0.78 | ATP6V1B1 (0.81) | ATP6V1B1ATP6AP1 | |
| SCHEMBL6291696 | 0.78 | ATP6V1B1 (0.81) | ATP6V1B1ATP6AP1 | |
| SCHEMBL8343613 | 0.78 | ATP6V1B1 (0.70) | ATP6V1B1ATP6AP1HSD17B10GAA | |
| SCHEMBL8343617 | 0.78 | ATP6V1B1 (0.70) | ATP6V1B1ATP6AP1HSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6903117-B2 | Indole derivatives for the treatment of osteoporosis | NIKEM RESEARCH S.R.L. (IT) | 2005-06-07 | — | — | US | claimed |
| US-6903117-B2 | Indole derivatives for the treatment of osteoporosis | NIKEM RESEARCH S.R.L. (IT) | 2005-06-07 | — | — | US | disclosed |