Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 1/20 | 0.51 |
| ▸ | FNTB | P49356 | 1/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 12/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 12/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 11/20 | 0.43 |
| ▸ | BCHE | P06276 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10192961 | 0.86 | FNTA (0.67) | FNTAFNTBBCHE | |
| SCHEMBL629755 | 0.85 | FNTA (0.47) | FNTAFNTB | |
| SCHEMBL7870255 | 0.85 | FNTA (0.43) | FNTAFNTB | |
| SCHEMBL7871123 | 0.82 | FNTA (0.69) | FNTAFNTB | |
| SCHEMBL7870322 | 0.81 | FNTA (0.52) | FNTAFNTBBCHE | |
| SCHEMBL10193212 | 0.81 | L3MBTL1 (0.47) | FNTAFNTB | |
| SCHEMBL7871098 | 0.81 | FNTA (0.49) | FNTAFNTBOPRM1OPRK1OPRD1 | |
| SCHEMBL6629277 | 0.80 | FNTA (0.79) | FNTAFNTB | |
| SCHEMBL630144 | 0.80 | FNTA (0.78) | FNTAFNTB | |
| SCHEMBL629652 | 0.80 | FNTA (0.44) | FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0986384-B1 | INHIBITORS OF PROTEIN ISOPRENYL TRANSFERASES | UNIV PITTSBURGH (US) | 2012-02-22 | — | — | EP | disclosed |
| EP-0986384-B1 | INHIBITORS OF PROTEIN ISOPRENYL TRANSFERASES | UNIV PITTSBURGH (US) | 2012-02-22 | — | — | EP | disclosed |
| US-6310095-B1 | INHIBITING OR TREATING CANCER, TREATING INTIMAL HYPERPLASIA ASSOCIATED WITH RESTENOSIS AND ATHEROSCLEROSIS, INHIBITING POST-TRANSLATIONAL MODIFICATION OF ONCOGENIC RAS PROTEIN BY PROTEIN FARNESYLTRANSFERASE AND/OR GERANYLGERANYLTRANSFERASE | UNIVERSITY OF PITTSBURGH | 2001-10-30 | — | — | US | disclosed |