SCHEMBL6296594

SCHEMBL6296594

C=Cc1ccc(CN(C)[Si](C)(C)C(C)(C)C)cc1

nearest known ligand 0.37

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.37
PYCR1 P32322 1/20 0.33
HRH3 Q9Y5N1 1/20 0.31
HDAC3 O15379 1/20 0.30
HDAC6 Q9UBN7 1/20 0.30
MEN1 O00255 1/20 0.30
TP53 P04637 1/20 0.30
MAPT P10636 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6293011 0.87 ALDH1A1 (0.37) ALDH1A1PYCR1HRH3HDAC3HDAC6
SCHEMBL610314 0.85 ALDH1A1 (0.38) ALDH1A1PYCR1MEN1TP53MAPT
SCHEMBL6293029 0.84 ALDH1A1 (0.34) ALDH1A1HRH3
SCHEMBL3840758 0.82 ALDH1A1 (0.42) ALDH1A1PYCR1HRH3HDAC3HDAC6
SCHEMBL6292994 0.82 ALDH1A1 (0.35) ALDH1A1
SCHEMBL6296597 0.81 TP53 (0.39) TP53
SCHEMBL609819 0.75 ALDH1A1 (0.35) ALDH1A1HRH3
SCHEMBL6292831 0.75 ALDH1A1 (0.35) ALDH1A1
SCHEMBL608738 0.74 ALDH1A1 (0.46) ALDH1A1PYCR1HRH3HDAC3HDAC6
SCHEMBL6292029 0.74 ALDH1A1 (0.34) ALDH1A1HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6838538-B2 Hydrogenated modified polymer, process for producing the same and composition containing the same JSR CORPORATION (JP) 2005-01-04 US disclosed
US-20030100683-A1 Hydrogenated modified polymer, process for producing the same and composition containing the same JSR CORPORATION (JP) 2003-05-29 US disclosed
EP-1245585-A2 Hydrogenated modified polymer, process for producing the same and composition containing the same JSR Corporation (JP) 2002-10-02 EP disclosed