Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 5/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11028375 | 1.00 | SLC18A3 (0.49) | SLC18A3AKR1C3AKR1C1CYP2D6CYP2C19 | |
| SCHEMBL6297981 | 1.00 | SLC18A3 (0.49) | SLC18A3AKR1C3AKR1C1CYP2D6CYP2C19 | |
| SCHEMBL10017976 | 0.92 | SLC18A3 (0.46) | SLC18A3AKR1C3AKR1C1CYP2D6CYP2C19 | |
| SCHEMBL779204 | 0.90 | SLC18A3 (0.47) | SLC18A3AKR1C3AKR1C1CYP2D6CYP2C19 | |
| SCHEMBL10347924 | 0.87 | SLC18A3 (0.55) | SLC18A3CYP2D6CYP2C19SIGMAR1CYP1A2 | |
| SCHEMBL11099008 | 0.87 | SLC18A3 (0.55) | SLC18A3CYP2D6CYP2C19SIGMAR1CYP1A2 | |
| SCHEMBL779924 | 0.87 | SLC18A3 (0.55) | SLC18A3CYP2D6CYP2C19SIGMAR1CYP1A2 | |
| SCHEMBL28132566 | 0.85 | SLC18A3 (0.49) | SLC18A3AKR1C3AKR1C1CYP2D6CYP2C19 | |
| SCHEMBL29215625 | 0.80 | SLC18A3 (0.57) | SLC18A3CYP2D6CYP2C19SIGMAR1CYP1A2 | |
| Biphenyl SCHEMBL10346569 | 0.80 | SLC18A3 (0.57) | SLC18A3CYP2D6CYP2C19SIGMAR1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6916513-B2 | High dielectric anisotropy and low birefringence; liquid crystal mixtures | MERCK PATENT GMBH (DE) | 2005-07-12 | — | — | US | disclosed |
| US-20040119050-A1 | liquid-crystal display element and an electro-optical display element. | MERCH PATENT GMBH (DE) | 2004-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040119050-A1 | liquid-crystal display element and an electro-optical display element. | CXCR1, DERL1, TTI2 | SLC18A3 2157/4885AKR1C3 3439/4885AKR1C1 3746/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.