SCHEMBL6299

SCHEMBL6299

N#CCc1ccccc1Br

nearest known ligand 0.48

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.48
CYP1A1 P04798 2/20 0.48
CYP1B1 Q16678 2/20 0.48
ALDH1A1 P00352 2/20 0.47
HPGD P15428 1/20 0.47
TAAR1 Q96RJ0 3/20 0.46
IDO1 P14902 2/20 0.45
CSNK2A1 P68400 3/20 0.40
PYCR1 P32322 1/20 0.40
TSHR P16473 2/20 0.38
CYP2A13 Q16696 1/20 0.37
MAPK1 P28482 1/20 0.36
CYP2D6 P10635 1/20 0.35
NFKB1 P19838 1/20 0.35
CYP2C19 P33261 1/20 0.35
HSD17B10 Q99714 1/20 0.35
LMNA P02545 1/20 0.35
CA12 O43570 1/20 0.35
CA2 P00918 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29446718 1.00 CYP1A2 (0.48) CYP1A2CYP1A1CYP1B1ALDH1A1HPGD
Ammonia Solution, Strong SCHEMBL28135352 0.98 CYP1A2 (0.46) CYP1A2CYP1A1CYP1B1ALDH1A1HPGD
SCHEMBL6333464 0.82 CYP1A1 (0.40) CYP1A2CYP1A1CYP1B1ALDH1A1HPGD
SCHEMBL1945874 0.82 ALDH1A1 (0.56) CYP1A2CYP1A1CYP1B1ALDH1A1HPGD
SCHEMBL29809738 0.82 ALDH1A1 (0.56) CYP1A2CYP1A1CYP1B1ALDH1A1HPGD
SCHEMBL28786179 0.80 ALDH1A1 (0.37) CYP1A2CYP1A1CYP1B1ALDH1A1HPGD
SCHEMBL333588 0.79 ALDH1A1 (0.38) CYP1A2CYP1A1CYP1B1ALDH1A1HPGD
SCHEMBL18190522 0.79 ALDH1A1 (0.38) CYP1A2CYP1A1CYP1B1ALDH1A1HPGD
SCHEMBL18190429 0.79 CSNK2A1 (0.39) CYP1A2CYP1A1CYP1B1ALDH1A1HPGD
SCHEMBL22904469 0.79 ALDH1A1 (0.38) CYP1A2CYP1A1CYP1B1ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 781 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122079996-A Pyrazolo [5,1-a ] isoindole derivative and synthetic method and application thereof 2026-05-26 CN claimed
CN-116478067-B Cyano-olefin solid luminescent material based on chiral binaphthyl skeleton, and preparation method and application thereof 曲阜师范大学 2024-11-08 CN claimed
CN-117903046-A Preparation method of anti-epileptic drug pirenzenenaphthalene 威海海洋职业学院 2024-04-19 CN claimed
CN-114605286-B Preparation method and application of pirenzepine intermediate 山东达因海洋生物制药股份有限公司 2023-09-08 CN claimed
CN-115651188-B RAFT chain transfer agent and preparation method and application thereof 南方科技大学 2023-09-05 CN claimed
CN-116478067-A Cyano-olefin solid luminescent material based on chiral binaphthyl skeleton, and preparation method and application thereof 曲阜师范大学 2023-07-25 CN claimed
CN-111196770-B Simple preparation method of bromfenac sodium 新发药业有限公司 2023-04-07 CN claimed
CN-115651188-A RAFT chain transfer agent, preparation method and application thereof 南方科技大学 2023-01-31 CN claimed
CN-112552154-B Preparation method of 1-bromofluorenone 河南省科学院化学研究所有限公司 2022-09-09 CN claimed
CN-112552154-A Preparation method of 1-bromofluorenone 河南省科学院化学研究所有限公司 2021-03-26 CN claimed
CN-101857517-A Method for preparing fluorobiaryl compound in pure water solution UNIV DALIAN TECH 2010-10-13 CN claimed
US-20100223716-A1 PROTECTIVE ARTICLES CONTAINING N-HALOCHITOSAN E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-09-09 US claimed
CN-101774871-A Method for preparing biaryl compound in pure water solution UNIV DALIAN TECH 2010-07-14 CN claimed
WO-2010011216-A1 N-ALKYLCHITOSAN FILMS AND LAMINATES MADE THEREFROM E.I. DU PONT DE NEMOURS AND COMPANY (US) 2010-01-28 WO claimed
US-20080289088-A1 N-ALKYLCHITOSAN FILMS AND LAMINATES MADE THEREFROM E.I. DU PONT DE NEMOURS AND COMPANY (US) 2008-11-27 US claimed
US-20080177110-A1 Processes for the synthesis of O-desmethylvenlafaxine TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) 2008-07-24 US claimed
EP-1917237-A2 PROCESSES FOR THE SYNTHESIS OF O-DESMETHYLVENLAFAXINE Teva Pharmaceutical Industries Ltd (IL) 2008-05-07 EP claimed
WO-2008013994-A2 PROCESSES FOR THE SYNTHESIS OF O-DESMETHYLVENLAFAXINE TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) 2008-01-31 WO claimed
US-20080020317-A1 Novel metal nanoparticle and formation of conductive pattern using the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2008-01-24 US claimed
US-20080003363-A1 Novel metal nanoparticle and method for formation of conductive pattern using the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2008-01-03 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080177110-A1 Processes for the synthesis of O-desmethylvenlafaxine CYP4F3, CYP3A4, CYP2D6 CYP1A2 17/4885CYP1A1 59/4885CYP1B1 83/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.