Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.44 |
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.41 |
| ▸ | GABRE | P78334 | 1/20 | 0.41 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.41 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.41 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.41 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8329965 | 0.80 | LMNA (0.50) | NPC1RAB9ALDHALMNAGAA | |
| SCHEMBL107259 | 0.80 | CSNK2A1 (0.59) | CSNK2A1KDM4ENFE2L2SMN1; SMN2MEN1 | |
| SCHEMBL30679777 | 0.80 | CSNK2A1 (0.59) | CSNK2A1KDM4ENFE2L2SMN1; SMN2MEN1 | |
| SCHEMBL6908325 | 0.78 | CSNK2A1 (0.57) | NPC1RAB9ACSNK2A1KDM4ENFE2L2 | |
| Bromide SCHEMBL6113400 | 0.78 | CSNK2A1 (0.57) | NPC1RAB9ACSNK2A1KDM4ENFE2L2 | |
| SCHEMBL6917296 | 0.78 | CSNK2A1 (0.57) | NPC1RAB9ACSNK2A1KDM4ENFE2L2 | |
| SCHEMBL6915319 | 0.78 | CSNK2A1 (0.57) | NPC1RAB9ACSNK2A1KDM4ENFE2L2 | |
| SCHEMBL6916723 | 0.78 | CSNK2A1 (0.57) | NPC1RAB9ACSNK2A1KDM4ENFE2L2 | |
| SCHEMBL6912721 | 0.78 | CSNK2A1 (0.57) | NPC1RAB9ACSNK2A1KDM4ENFE2L2 | |
| Charcoal, Activated SCHEMBL7747676 | 0.78 | CSNK2A1 (0.57) | NPC1RAB9ACSNK2A1KDM4ENFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8168638-B2 | Pyrazinecarboxamide derivatives and plant disease controlling agents containing the same | NIHON NOHYAKU CO., LTD. (JP) | 2012-05-01 | — | — | US | disclosed |
| EP-1963286-B1 | PYRAZINECARBOXAMIDE DERIVATIVES AND PLANT DISEASE CONTROLLING AGENTS CONTAINING THE SAME | NIHON NOHYAKU CO LTD (JP) | 2012-02-22 | — | — | EP | disclosed |
| US-20090233934-A1 | Pyrazinecarboxamide Derivatives and Plant Disease Controlling Agents Containing the Same | NIHON NOHYAKU CO., LTD. (JP) | 2009-09-17 | — | — | US | disclosed |
| EP-1963286-A1 | PYRAZINECARBOXAMIDE DERIVATIVES AND PLANT DISEASE CONTROLLING AGENTS CONTAINING THE SAME | Nihon Nohyaku Co., Ltd. (JP) | 2008-09-03 | — | — | EP | disclosed |
| WO-2007072999-A1 | PYRAZINECARBOXAMIDE DERIVATIVES AND PLANT DISEASE CONTROLLING AGENTS CONTAINING THE SAME | NIHON NOHYAKU CO., LTD (JP) | 2007-06-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090233934-A1 | Pyrazinecarboxamide Derivatives and Plant Disease Controlling Agents Containing the Same | CBR3, CNPY2, AADAC | NPC1 1151/4885RAB9A 2534/4885KDM4C 349/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.