Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 9/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CSF1R | P07333 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | PTGES | O14684 | 3/20 | 0.45 |
| ▸ | GRM6 | O15303 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6300618 | 0.89 | ALOX5 (0.60) | ALOX5KMT2AMEN1MAPTRXFP1 | |
| SCHEMBL6295738 | 0.89 | ALOX5 (0.60) | ALOX5NPC1KMT2AMEN1MAPT | |
| SCHEMBL6295917 | 0.88 | ALOX5 (0.59) | ALOX5NPC1KMT2AMEN1MAPT | |
| SCHEMBL6294584 | 0.87 | ALOX5 (0.57) | ALOX5NPC1KMT2AMEN1MAPT | |
| SCHEMBL6294686 | 0.86 | KDM4E (0.64) | ALOX5NPC1KMT2AMEN1MAPT | |
| SCHEMBL6295986 | 0.83 | KDM4E (0.51) | KMT2AKDM4EALDH1A1LMNAGAA | |
| SCHEMBL6295733 | 0.83 | ALOX5 (0.58) | ALOX5NPC1KMT2AMEN1MAPT | |
| SCHEMBL6295720 | 0.83 | ALOX5 (0.54) | ALOX5NPC1KMT2AMEN1MAPT | |
| SCHEMBL6295739 | 0.80 | ALOX5 (0.58) | ALOX5KMT2AMEN1MAPTKDM4E | |
| SCHEMBL22877730 | 0.80 | NPC1 (0.46) | ALOX5NPC1KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6897316-B2 | Substituted 2-phenyl-4-quinolone-3-carboxylic acid compounds and their use as antitumor agents | CHINA MEDICAL UNIVERSITY (TW) | 2005-05-24 | — | — | US | disclosed |