Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.53 |
| ▸ | ESR1 | P03372 | 3/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.39 |
| ▸ | MME | P08473 | 2/20 | 0.39 |
| ▸ | ACE | P12821 | 2/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.38 |
| ▸ | CPA1 | P15085 | 1/20 | 0.38 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6300611 | 1.00 | SLC7A5 (0.53) | SLC7A5ESR1ESR2FOLH1TAAR1 | |
| SCHEMBL7163410 | 0.85 | SLC7A5 (0.58) | SLC7A5ESR1ESR2FOLH1TAAR1 | |
| SCHEMBL7163413 | 0.85 | SLC7A5 (0.58) | SLC7A5ESR1ESR2FOLH1TAAR1 | |
| SCHEMBL276571 | 0.83 | SLC7A5 (0.55) | SLC7A5ESR1ESR2FOLH1TAAR1 | |
| SCHEMBL276572 | 0.83 | SLC7A5 (0.55) | SLC7A5ESR1ESR2FOLH1TAAR1 | |
| SCHEMBL7373699 | 0.82 | SLC7A5 (0.54) | SLC7A5ESR1ESR2FOLH1TAAR1 | |
| SCHEMBL2522740 | 0.82 | SLC7A5 (0.54) | SLC7A5ESR1ESR2FOLH1TAAR1 | |
| SCHEMBL31127604 | 0.82 | SLC7A5 (0.54) | SLC7A5ESR1ESR2FOLH1TAAR1 | |
| SCHEMBL29278381 | 0.81 | SLC7A5 (0.53) | SLC7A5ESR1ESR2FOLH1TAAR1 | |
| SCHEMBL6300076 | 0.81 | SLC7A5 (0.53) | SLC7A5ESR1ESR2FOLH1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6939716-B2 | Method for detecting conditions indicative of sepsis | WASHINGTON UNIVERSITY (US) | 2005-09-06 | — | — | US | disclosed |
| EP-1427845-A2 | METHOD FOR DETECTING SEPSIS | Washington University (US) | 2004-06-16 | — | — | EP | disclosed |
| US-20030100122-A1 | Method for detecting conditions indicative of sepsis | WASHINGTON UNIVERSITY | 2003-05-29 | — | — | US | disclosed |
| WO-2003025212-A2 | METHOD FOR DETECTING SEPSIS | WASHINGTON UNIVERSITY (US) | 2003-03-27 | — | — | WO | disclosed |
| WO-1990015993-A1 | ASSAY FOR HUMAN VENTRICULAR MYOSIN LC1 AND MONOCLONAL ANTIBODY THERETO | THE GENERAL HOSPITAL CORPORATION (US) | 1990-12-27 | — | — | WO | disclosed |