Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F3 | P13726 | 19/20 | 0.55 |
| ▸ | F2 | P00734 | 18/20 | 0.55 |
| ▸ | F7 | P08709 | 15/20 | 0.54 |
| ▸ | F10 | P00742 | 15/20 | 0.54 |
| ▸ | PLG | P00747 | 7/20 | 0.54 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.53 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.53 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8498736 | 0.95 | F3 (0.59) | F3F2F7F10PLG | |
| SCHEMBL8506173 | 0.88 | F7 (0.65) | F3F2F7F10PLG | |
| Trifluoroacetic Acid SCHEMBL6296048 | 0.84 | F3 (0.54) | F3F2F7F10PLG | |
| Trifluoroacetic Acid SCHEMBL7157111 | 0.83 | F3 (0.53) | F3F2F7F10PLG | |
| Trifluoroacetic Acid SCHEMBL7152805 | 0.80 | F3 (0.48) | F3F2F7F10PLG | |
| Trifluoroacetic Acid SCHEMBL7156665 | 0.79 | F3 (0.49) | F3F2F7F10PLG | |
| SCHEMBL8506169 | 0.79 | F3 (0.57) | F3F2F7F10PLG | |
| SCHEMBL6300738 | 0.76 | F3 (0.41) | F3F2F7F10PLG | |
| SCHEMBL7664577 | 0.74 | F7 (0.82) | F3F2F7F10PLG | |
| SCHEMBL7652338 | 0.72 | F7 (0.68) | F3F2F7F10PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6916837-B2 | Amidino derivatives and anticoagulants and thrombosis therapeutic agents containing them | EISAI CO., LTD. (JP) | 2005-07-12 | — | — | US | disclosed |
| US-20030181766-A1 | Amidino derivatives, and anticoagulants and thrombosis therapeutic agents containing them | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2003-09-25 | — | — | US | disclosed |
| EP-1312602-A1 | Amidino derivatives, and anticoagulants and thrombosis therapeutic agents containing them | Eisai Co., Ltd. (JP) | 2003-05-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030181766-A1 | Amidino derivatives, and anticoagulants and thrombosis therapeutic agents containing them | F2, SERPINC1, F12 | F3 56/4885F2 1/4885F7 22/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.