Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 3/20 | 0.45 |
| ▸ | F10 | P00742 | 7/20 | 0.45 |
| ▸ | F3 | P13726 | 13/20 | 0.43 |
| ▸ | F7 | P08709 | 5/20 | 0.41 |
| ▸ | F2 | P00734 | 9/20 | 0.41 |
| ▸ | TMPRSS6 | Q8IU80 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7153773 | 0.93 | F10 (0.48) | BRD4F10F3F7F2 | |
| Trifluoroacetic Acid SCHEMBL7151193 | 0.90 | PRSS1 (0.51) | F10F3F2TMPRSS6 | |
| SCHEMBL6300739 | 0.89 | F10 (0.45) | BRD4F10F2TMPRSS6 | |
| Trifluoroacetic Acid SCHEMBL7154778 | 0.89 | PLA2G7 (0.46) | F10F3F7F2TMPRSS6 | |
| Trifluoroacetic Acid SCHEMBL7155325 | 0.88 | F2 (0.47) | F10F3F7F2TMPRSS6 | |
| Trifluoroacetic Acid SCHEMBL6300672 | 0.88 | F10 (0.48) | F10F3F7F2 | |
| Trifluoroacetic Acid SCHEMBL7153335 | 0.85 | BRD4 (0.51) | BRD4F10F3F7F2 | |
| Trifluoroacetic Acid SCHEMBL7153982 | 0.85 | F10 (0.47) | BRD4F10F3F7F2 | |
| Trifluoroacetic Acid SCHEMBL6296048 | 0.84 | F3 (0.54) | F10F3F7F2 | |
| SCHEMBL6294700 | 0.84 | PRSS1 (0.55) | F10F2TMPRSS6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6916837-B2 | Amidino derivatives and anticoagulants and thrombosis therapeutic agents containing them | EISAI CO., LTD. (JP) | 2005-07-12 | — | — | US | disclosed |
| EP-1312602-A1 | Amidino derivatives, and anticoagulants and thrombosis therapeutic agents containing them | Eisai Co., Ltd. (JP) | 2003-05-21 | — | — | EP | disclosed |