Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G7 | Q13093 | 4/20 | 0.44 |
| ▸ | CCR1 | P32246 | 2/20 | 0.44 |
| ▸ | CCR2 | P41597 | 2/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.43 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.43 |
| ▸ | F10 | P00742 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.42 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.41 |
| ▸ | ACLY | P53396 | 1/20 | 0.41 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.41 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.41 |
| ▸ | BRAF | P15056 | 1/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7157714 | 0.98 | PLA2G7 (0.42) | PLA2G7CCR1CCR2PRSS1PRSS2 | |
| SCHEMBL6295821 | 0.92 | PLA2G7 (0.44) | PLA2G7PRSS1PRSS2PRSS3ST14 | |
| Trifluoroacetic Acid SCHEMBL7154045 | 0.92 | PLA2G7 (0.43) | PLA2G7PRSS1PRSS2PRSS3ST14 | |
| Trifluoroacetic Acid SCHEMBL7158713 | 0.91 | F2 (0.48) | PLA2G7PRSS1PRSS2PRSS3ST14 | |
| Trifluoroacetic Acid SCHEMBL7158686 | 0.90 | F2 (0.45) | PLA2G7PRSS1PRSS2PRSS3ST14 | |
| Trifluoroacetic Acid SCHEMBL7158329 | 0.90 | PLA2G7 (0.42) | PLA2G7PRSS1PRSS2PRSS3ST14 | |
| Trifluoroacetic Acid SCHEMBL7157101 | 0.90 | PLA2G7 (0.44) | PLA2G7PRSS1PRSS2PRSS3ST14 | |
| SCHEMBL6295817 | 0.90 | PLA2G7 (0.46) | PLA2G7PRSS1PRSS2PRSS3ST14 | |
| Trifluoroacetic Acid SCHEMBL7156270 | 0.89 | PLA2G7 (0.55) | PLA2G7F10F2TMPRSS6ALOX15 | |
| Trifluoroacetic Acid SCHEMBL6294978 | 0.88 | F2 (0.49) | PLA2G7PRSS1PRSS2PRSS3ST14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6916837-B2 | Amidino derivatives and anticoagulants and thrombosis therapeutic agents containing them | EISAI CO., LTD. (JP) | 2005-07-12 | — | — | US | disclosed |