Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.42 |
| ▸ | VDR | P11473 | 3/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.42 |
| ▸ | AGTR1 | P30556 | 4/20 | 0.40 |
| ▸ | AGTR2 | P50052 | 4/20 | 0.40 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.40 |
| ▸ | UBE2N | P61088 | 1/20 | 0.40 |
| ▸ | GALR3 | O60755 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6303584 | 0.96 | PPARG (0.56) | PPARGALOX5APVDRNR1H4AGTR1 | |
| SCHEMBL6301607 | 0.95 | PPARG (0.58) | PPARGAGTR1AGTR2TSHR | |
| SCHEMBL6308005 | 0.94 | PPARG (0.57) | PPARGAGTR1AGTR2TSHR | |
| SCHEMBL6303646 | 0.94 | PPARG (0.57) | PPARGAGTR1AGTR2TSHR | |
| SCHEMBL6301337 | 0.92 | PPARG (0.51) | PPARGALOX5APVDRNR1H4DCTPP1 | |
| SCHEMBL6303322 | 0.91 | PPARG (0.49) | PPARGALOX5APDCTPP1PIN1 | |
| SCHEMBL6301570 | 0.90 | PPARG (0.51) | PPARGKMT2AALOX5APDCTPP1GALR3 | |
| SCHEMBL7651488 | 0.90 | MAPK1 (0.46) | PPARGKMT2AALOX5APVDRNR1H4 | |
| SCHEMBL6308619 | 0.88 | DCTPP1 (0.51) | PPARGALOX5APAGTR1AGTR2DCTPP1 | |
| SCHEMBL6308646 | 0.87 | PPARG (0.56) | PPARGALOX5APDCTPP1GALR3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6869950-B1 | Benzimidazole derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-03-22 | — | — | US | disclosed |
| EP-1142880-A1 | BENZIMIDAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-10-10 | — | — | EP | disclosed |