Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 3/20 | 0.39 |
| ▸ | CNR2 | P34972 | 3/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28108218 | 0.83 | SLC6A4 (0.51) | ALDH1A1CYP1A2CYP2C9CYP2C19KDM4E | |
| SCHEMBL10763023 | 0.81 | KDM4E (0.46) | ALDH1A1CYP1A2CYP2C9CYP2C19KDM4E | |
| SCHEMBL10580910 | 0.81 | ALDH1A1 (0.44) | ALDH1A1CYP1A2CYP2C9CYP2C19KDM4E | |
| SCHEMBL10580276 | 0.81 | KDM4E (0.46) | ALDH1A1CYP1A2CYP2C9CYP2C19KDM4E | |
| SCHEMBL10583531 | 0.81 | KDM4E (0.46) | ALDH1A1CYP1A2CYP2C9CYP2C19KDM4E | |
| SCHEMBL10580483 | 0.81 | KDM4E (0.46) | ALDH1A1CYP1A2CYP2C9CYP2C19KDM4E | |
| SCHEMBL10579678 | 0.81 | KDM4E (0.46) | ALDH1A1CYP1A2CYP2C9CYP2C19KDM4E | |
| SCHEMBL10580858 | 0.81 | KDM4E (0.46) | ALDH1A1CYP1A2CYP2C9CYP2C19KDM4E | |
| SCHEMBL10580574 | 0.81 | KDM4E (0.46) | ALDH1A1CYP1A2CYP2C9CYP2C19KDM4E | |
| SCHEMBL7379765 | 0.81 | PPARG (0.46) | ALDH1A1CYP1A2CYP2C9CYP2C19KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6869950-B1 | Benzimidazole derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-03-22 | — | — | US | disclosed |
| EP-1142880-A1 | BENZIMIDAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-10-10 | — | — | EP | disclosed |