SCHEMBL6301508

SCHEMBL6301508

CCCCS(=O)(=O)Nc1cccc(O)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AURKA O14965 2/20 0.53
KDR P35968 2/20 0.53
AURKB Q96GD4 2/20 0.53
MAP1LC3B Q9GZQ8 2/20 0.53
MAP1LC3A Q9H492 1/20 0.53
BRD4 O60885 3/20 0.51
AR P10275 1/20 0.50
HSD17B2 P37059 3/20 0.49
PGAM1 P18669 1/20 0.47
LMNA P02545 2/20 0.47
HPGD P15428 2/20 0.47
UQCRB P14927 1/20 0.47
ALDH1A1 P00352 3/20 0.46
KDM4E B2RXH2 2/20 0.46
HTT P42858 1/20 0.46
HSD17B10 Q99714 1/20 0.45
HSD17B1 P14061 1/20 0.45
CYP1A2 P05177 1/20 0.44
PDE5A O76074 1/20 0.43
PDE1A P54750 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6295432 0.94 MAP1LC3B (0.48) AURKAKDRAURKBMAP1LC3BMAP1LC3A
SCHEMBL10884996 0.94 MAP1LC3B (0.48) AURKAKDRAURKBMAP1LC3BMAP1LC3A
SCHEMBL8756642 0.94 MAP1LC3B (0.48) AURKAKDRAURKBMAP1LC3BMAP1LC3A
SCHEMBL28216263 0.90 HSD17B2 (0.51) AURKAKDRAURKBMAP1LC3BBRD4
SCHEMBL11126460 0.85 HSD17B2 (0.55) AURKAKDRAURKBMAP1LC3BMAP1LC3A
SCHEMBL10345020 0.83 BRD4 (0.52) AURKAKDRAURKBMAP1LC3BMAP1LC3A
SCHEMBL8861660 0.83 BRD4 (0.52) AURKAKDRAURKBMAP1LC3BMAP1LC3A
SCHEMBL14583304 0.83 BRD4 (0.52) AURKAKDRAURKBBRD4AR
SCHEMBL20372960 0.81 BRD4 (0.51) AURKAKDRAURKBMAP1LC3BMAP1LC3A
SCHEMBL16868357 0.81 AR (0.53) AURKAKDRAURKBBRD4AR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6921740-B1 Electron-receiving compound and thermal recording material MITSUBISHI PAPER MIILS LTD. (JP) 2005-07-26 US disclosed
US-6579829-B2 Aromatic sulfonamide compound MITSUI CHEMICALS, INC. (JP) 2003-06-17 US disclosed
EP-1138517-A2 Developer composition and heat sensitive recording material Mitsui Chemicals, Inc. (JP) 2001-10-04 EP disclosed
US-5630927-A DEVELOPMENT INHIBITOR RELEASING COUPLERS, COLOR FILMS, IMPROVED SHARPNESS, GRAININESS, STORAGE STABILITY, COLOR REPRODUCIBILITY FUJI PHOTO FILM CO., LTD. (JP) 1997-05-20 US disclosed
EP-0330043-B1 Method for processing silver halide color photographic material FUJI PHOTO FILM CO LTD (JP) 1996-01-17 EP disclosed
EP-0326160-B1 Silver halide photographic material FUJI PHOTO FILM CO LTD (JP) 1995-12-27 EP disclosed
EP-0346498-B1 PROCESS FOR PROCESSING SILVER HALIDE COLOR PHOTOGRAPHIC MATERIALS FUJI PHOTO FILM CO LTD (JP) 1994-11-30 EP disclosed
US-5204213-A Compound yielding photographically useful group, s torage stable FUJI PHOTO FILM CO., LTD. (JP) 1993-04-20 US disclosed
US-5155016-A Silver halide color photographic material containing novel pyrazoloazole coupler and method to produce color image FUJI PHOTO FILM CO., LTD. (JP) 1992-10-13 US disclosed
US-5059514-A Bleaching using promoter and subjecting waste liquid to anionic exchange resin FUJI PHOTO FILM CO., LTD. (JP) 1991-10-22 US disclosed
US-H953-H Using acidic bleaching bath containing iron complex salt and fixing bath with specific additives FUJI PHOTO FILM CO., LTD. (JP) 1991-08-06 US disclosed
US-5021329-A Colorless until exposed to produce a cye having a hue suitable for color masking when developed; high photosensitivity; improved color reproduction FUJI PHOTO FILM CO., LTD. (JP) 1991-06-04 US disclosed
US-5002860-A Development of a silver halide photographic material with a solution having bleaching ability, complexes of iron with diaminetetraacetic acid derivatives FUJI PHOTO FILM CO., LTD. (JP) 1991-03-26 US disclosed
US-4963474-A DEVELOPMENT AFTERTREATMENT IN BLEACHING AND FIXING BATH FUJI PHOTO FILM CO., LTD. (JP) 1990-10-16 US disclosed
EP-0346498-A1 PROCESS FOR PROCESSING SILVER HALIDE COLOR PHOTOGRAPHIC MATERIALS FUJI PHOTO FILM CO., LTD. (JP) 1989-12-20 EP disclosed
EP-0326160-A2 Silver halide photographic material FUJI PHOTO FILM CO., LTD. (JP) 1989-08-02 EP disclosed