Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 5/20 | 0.44 |
| ▸ | SHBG | P04278 | 2/20 | 0.38 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MBOAT4 | Q96T53 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9948621 | 0.89 | CYP19A1 (0.44) | CYP19A1SHBGSERPINA6ALDH1A1SLC22A1 | |
| SCHEMBL4013302 | 0.86 | CYP19A1 (0.44) | CYP19A1SHBGSERPINA6ALDH1A1SLC22A1 | |
| SCHEMBL3356884 | 0.85 | CYP19A1 (0.44) | CYP19A1SHBGSERPINA6ALDH1A1SLC22A1 | |
| SCHEMBL9947825 | 0.83 | CYP19A1 (0.42) | CYP19A1SHBGSERPINA6ALDH1A1SLC22A1 | |
| SCHEMBL9948717 | 0.82 | CYP19A1 (0.41) | CYP19A1SHBGSERPINA6ALDH1A1SLC22A1 | |
| SCHEMBL10449144 | 0.80 | CYP19A1 (0.39) | CYP19A1SHBGSERPINA6ALDH1A1SLC22A1 | |
| SCHEMBL9948095 | 0.80 | CYP19A1 (0.39) | CYP19A1SHBGSERPINA6ALDH1A1SLC22A1 | |
| SCHEMBL6244889 | 0.80 | CYP19A1 (0.39) | CYP19A1SHBGSERPINA6ALDH1A1SLC22A1 | |
| SCHEMBL4220650 | 0.78 | CYP19A1 (0.45) | CYP19A1SHBGSERPINA6ALDH1A1SLC22A1 | |
| SCHEMBL11977689 | 0.77 | CYP19A1 (0.66) | CYP19A1SHBGSERPINA6ALDH1A1SLC22A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6855836-B2 | 17-Methylene steroids, process for their production and pharmaceutical compositions that contain these compounds | JENAPHARM GMBH & CO. KG (DE) | 2005-02-15 | — | — | US | disclosed |