Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.66 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | SHBG | P04278 | 2/20 | 0.62 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.62 |
| ▸ | THRB | P10828 | 1/20 | 0.62 |
| ▸ | PGR | P06401 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | ESR1 | P03372 | 1/20 | 0.56 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.56 |
| ▸ | AR | P10275 | 3/20 | 0.55 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL922877 | 1.00 | CYP19A1 (0.66) | CYP19A1SERPINA6ALDH1A1SHBGSLC22A1 | |
| SCHEMBL19608861 | 1.00 | CYP19A1 (0.66) | CYP19A1SERPINA6ALDH1A1SHBGSLC22A1 | |
| SCHEMBL26425075 | 1.00 | CYP19A1 (0.66) | CYP19A1SERPINA6ALDH1A1SHBGSLC22A1 | |
| SCHEMBL13216466 | 1.00 | CYP19A1 (0.66) | CYP19A1SERPINA6ALDH1A1SHBGSLC22A1 | |
| Cyclohexane Propionic Acid SCHEMBL27589911 | 0.84 | SERPINA6 (0.49) | CYP19A1SERPINA6ALDH1A1SHBGSLC22A1 | |
| SCHEMBL9116613 | 0.82 | CYP19A1 (0.60) | CYP19A1SERPINA6ALDH1A1SHBGSLC22A1 | |
| SCHEMBL11795958 | 0.81 | AR (0.64) | CYP19A1SERPINA6ALDH1A1SHBGSLC22A1 | |
| SCHEMBL9948814 | 0.81 | CYP19A1 (0.44) | CYP19A1SERPINA6ALDH1A1SHBGSLC22A1 | |
| SCHEMBL9948623 | 0.81 | CYP19A1 (0.44) | CYP19A1SERPINA6ALDH1A1SHBGSLC22A1 | |
| SCHEMBL24102654 | 0.80 | PGR (0.56) | CYP19A1SERPINA6ALDH1A1SHBGSLC22A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015181391-A1 | METHOD FOR THE DIAGNOSIS OF ALZHEIMER'S DISEASE AND MILD COGNITIVE IMPAIRMENT | BIOCROSS, S.L. (ES) | 2015-12-03 | — | — | WO | disclosed |
| US-8236565-B2 | Tagging reagents and methods for hydroxylated compounds | DH TECHNOLOGIES DEVELOPMENT PTE. LTD. (SG) | 2012-08-07 | — | — | US | disclosed |
| US-20080014642-A1 | TAGGING REAGENTS AND METHODS FOR HYDROXYLATED COMPOUNDS | APPLIED BIOSYSTEMS, INC. (US) | 2008-01-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080014642-A1 | TAGGING REAGENTS AND METHODS FOR HYDROXYLATED COMPOUNDS | DHCR7, SRMS, CYP21A2 | CYP19A1 42/4885SERPINA6 279/4885ALDH1A1 1485/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.