Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 12/20 | 0.56 |
| ▸ | ITGA5 | P08648 | 3/20 | 0.56 |
| ▸ | ITGA4 | P13612 | 7/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | ITGB7 | P26010 | 3/20 | 0.51 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.49 |
| ▸ | ITGAV | P06756 | 4/20 | 0.48 |
| ▸ | BDKRB1 | P46663 | 3/20 | 0.46 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.46 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.46 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL630187 | 1.00 | ITGB1 (0.56) | ITGB1ITGA5ITGA4POLBITGB7 | |
| SCHEMBL5172120 | 0.92 | ITGB1 (0.55) | ITGB1ITGA5ITGA4POLBITGB7 | |
| SCHEMBL5172768 | 0.91 | POLB (0.53) | ITGB1ITGA5ITGA4POLBITGB7 | |
| SCHEMBL630087 | 0.91 | POLB (0.56) | ITGB1ITGA5ITGA4POLBITGB7 | |
| SCHEMBL630086 | 0.91 | POLB (0.56) | ITGB1ITGA5ITGA4POLBITGB7 | |
| SCHEMBL2977265 | 0.91 | POLB (0.53) | ITGB1ITGA5ITGA4POLBITGB7 | |
| SCHEMBL2977267 | 0.91 | POLB (0.53) | ITGB1ITGA5ITGA4POLBITGB7 | |
| SCHEMBL6367902 | 0.91 | ITGB1 (0.59) | ITGB1ITGA5ITGA4POLBITGB7 | |
| SCHEMBL13206952 | 0.90 | POLB (0.49) | ITGB1ITGA5ITGA4POLBITGB7 | |
| SCHEMBL629838 | 0.90 | KCNQ1 (0.62) | ITGB1ITGA5ITGA4POLBITGB7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778637-B1 | FKBP-binding composition and pharmaceutical use thereof | AVENTIS PHARMA INC (US) | 2012-02-22 | — | — | EP | disclosed |