Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.80 |
| ▸ | NPC1 | O15118 | 4/20 | 0.80 |
| ▸ | RAB9A | P51151 | 3/20 | 0.80 |
| ▸ | PKM | P14618 | 1/20 | 0.80 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.80 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.68 |
| ▸ | HPGD | P15428 | 3/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.68 |
| ▸ | CA1 | P00915 | 1/20 | 0.64 |
| ▸ | CA2 | P00918 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 3/20 | 0.60 |
| ▸ | KDR | P35968 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.59 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.59 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6297231 | 0.89 | MAPT (0.84) | MAPTNPC1RAB9APKMPAX8 | |
| SCHEMBL6295855 | 0.87 | MAPT (0.67) | MAPTNPC1RAB9APKMPAX8 | |
| SCHEMBL30542218 | 0.84 | ALDH1A1 (0.73) | MAPTNPC1RAB9APKMALDH1A1 | |
| SCHEMBL5078630 | 0.84 | ALDH1A1 (0.79) | MAPTNPC1RAB9APKMALDH1A1 | |
| SCHEMBL11517562 | 0.84 | CA1 (0.71) | NPC1RAB9AALDH1A1HPGDKDM4E | |
| SCHEMBL4446011 | 0.83 | MEN1 (0.76) | MAPTNPC1RAB9APKMPAX8 | |
| SCHEMBL13279936 | 0.83 | MAPT (0.74) | MAPTNPC1RAB9APKMPAX8 | |
| Hydrochloric Acid SCHEMBL2106771 | 0.82 | MEN1 (0.74) | MAPTNPC1RAB9APKMPAX8 | |
| SCHEMBL5452814 | 0.82 | KMT2A (0.64) | MAPTNPC1RAB9APKMPAX8 | |
| SCHEMBL30542203 | 0.81 | ALDH1A1 (0.65) | MAPTNPC1RAB9APKMPAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6875764-B1 | Urea and thiourea compounds useful for treatment of coccidiosis | NEW PHARMA RESEARCH SWEDEN AB (SE) | 2005-04-05 | — | — | US | disclosed |
| EP-1224165-A1 | NOVEL COMPOUNDS | New Pharma Research Sweden AB (SE) | 2002-07-24 | — | — | EP | disclosed |
| WO-2001030749-A1 | NOVEL COMPOUNDS | NEW PHARMA RESEARCH SWEDEN AB (SE) | 2001-05-03 | — | — | WO | disclosed |