SCHEMBL630209

SCHEMBL630209

NC(Cc1ccc(O)cc1)C(=O)OCc1ccccc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 2/20 0.62
ALPI P09923 1/20 0.56
PKM P14618 1/20 0.56
PTGS1 P23219 1/20 0.56
XIAP P98170 1/20 0.56
SLC15A1 P46059 2/20 0.55
LTA4H P09960 1/20 0.55
LAP3 P28838 1/20 0.55
LMNA P02545 1/20 0.54
ALDH1A1 P00352 2/20 0.51
HDAC8 Q9BY41 2/20 0.51
TYR P14679 1/20 0.50
ERAP2 Q6P179 1/20 0.49
LNPEP Q9UIQ6 1/20 0.49
CA12 O43570 1/20 0.48
AKR1B10 O60218 1/20 0.48
AKR1B1 P15121 1/20 0.48
CA4 P22748 1/20 0.48
CA6 P23280 1/20 0.48
CA5A P35218 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16080193 1.00 SLC7A5 (0.62) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL25982889 1.00 SLC7A5 (0.62) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL121369 1.00 SLC7A5 (0.62) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL26023571 1.00 SLC7A5 (0.62) SLC7A5ALPIPKMPTGS1XIAP
Hydrochloric Acid SCHEMBL9831417 0.98 SLC7A5 (0.60) SLC7A5ALPIPKMPTGS1XIAP
Hydrochloric Acid SCHEMBL9831421 0.98 SLC7A5 (0.60) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL8030938 0.95 SLC7A5 (0.57) SLC7A5ALPIPKMPTGS1XIAP
Hydrochloric Acid SCHEMBL8030935 0.94 SLC7A5 (0.55) SLC7A5ALPIPKMPTGS1XIAP
Methoxymethane SCHEMBL9818529 0.94 SLC7A5 (0.55) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL8012238 0.93 SLC7A5 (0.65) SLC7A5SLC15A1LTA4HLAP3HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 184 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3634944-B1 SYNTHESIS OF TYROSINE DERIVED DIPHENOL MONOMERS MEDTRONIC INC (US) 2022-06-29 EP claimed
CN-107556438-B Multi-responsive cross-linked polymer, drug-loaded nano micelle and preparation method thereof 西南民族大学 2020-05-12 CN claimed
EP-3634944-A1 SYNTHESIS OF TYROSINE DERIVED DIPHENOL MONOMERS Medtronic, Inc. (US) 2020-04-15 EP claimed
US-10442757-B2 Synthesis of tyrosine derived diphenol monomers MEDTRONIC, INC. (US) 2019-10-15 US claimed
US-20180354892-A1 SYNTHESIS OF TYROSINE DERIVED DIPHENOL MONOMERS TYRX, INC. (US) 2018-12-13 US claimed
WO-2018226340-A1 SYNTHESIS OF TYROSINE DERIVED DIPHENOL MONOMERS TYRX, INC. (US) 2018-12-13 WO claimed
CN-102250202-B 1-paranitrophenyl-beta-carboline-3-formyl amine acid carbamates and synthesis method and use thereof UNIV CAPITAL MEDICAL SCIENCES 2013-08-28 CN claimed
CN-102241674-B Synthesis method and antitumor activity evaluation of 1,1-dimethyl-beta-carboline-3-formacyl amino acid benzyl ester UNIV CAPITAL MEDICAL 2012-09-12 CN claimed
CN-101906102-B Beta-carboline alkaloid derivative, preparation method and application thereof UNIV CAPITAL MEDICAL 2012-08-29 CN claimed
CN-102250202-A 1-paranitrophenyl-beta-carboline-3-formyl amine acid carbamates and synthesis method and use thereof UNIV CAPITAL MEDICAL 2011-11-23 CN claimed
CN-102241674-A Synthesis method and antitumor activity evaluation of 1,1-dimethyl-beta-carboline-3-formacyl amino acid benzyl ester UNIV CAPITAL MEDICAL 2011-11-16 CN claimed
CN-101497615-B Substituted purine, preparation and use in medicine ZHEJIANG MED XINCHANG PHARM 2010-12-15 CN claimed
CN-101906102-A Beta-carboline alkaloid derivative, preparation method and application thereof UNIV CAPITAL MEDICAL 2010-12-08 CN claimed
CN-101597289-A 2-tryptophyl-beta-tetrahydro carboline-3-formyol amino-acid benzyl ester and its production and application UNIV CAPITAL MEDICAL (CN) 2009-12-09 CN claimed
CN-101597290-A β-Ka Lin-3-formyl tryptophyl amino-acid benzyl ester and its production and application UNIV CAPITAL MEDICAL (CN) 2009-12-09 CN claimed
CN-101497615-A Substituted purine, preparation and use in medicine XINCHANG PHARMACEUTICAL FACTORY ZHEJIANG MEDICINE CO LTD (CN) 2009-08-05 CN claimed
US-20240399776-A1 COLOR DEVELOPER, THERMAL RECORDING MATERIAL, AND THERMAL RECORDING LAYER COATING MATERIAL SANKO CO., LTD. (JP) 2024-12-05 US disclosed
CN-118851976-A Hexokinase inhibitor, ruthenium complex of hexokinase inhibitor and application of ruthenium complex in preparation of antitumor drugs 首都医科大学 2024-10-29 CN disclosed
EP-0539848-A1 N-(mercaptoacyl)amino acids, methods of their preparation and therapeutic use, and pharmaceutical compositions containing them INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) 1993-05-05 EP disclosed
WO-1993008162-A1 N-(MERCAPTOACYL)AMINO ACIDS, METHODS OF THEIR PREPARATION AND THERAPEUTIC USE, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) 1993-04-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10442757-B2 Synthesis of tyrosine derived diphenol monomers TYR, TH, TYRO3 SLC7A5 1220/4885ALPI 617/4885PKM 1774/4885
US-20180354892-A1 SYNTHESIS OF TYROSINE DERIVED DIPHENOL MONOMERS TYR, TH, DDT SLC7A5 1198/4885ALPI 3122/4885PKM 1537/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.