SCHEMBL121369

SCHEMBL121369

N[C@@H](Cc1ccc(O)cc1)C(=O)OCc1ccccc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 2/20 0.62
ALPI P09923 1/20 0.56
PKM P14618 1/20 0.56
PTGS1 P23219 1/20 0.56
XIAP P98170 1/20 0.56
SLC15A1 P46059 2/20 0.55
LTA4H P09960 1/20 0.55
LAP3 P28838 1/20 0.55
LMNA P02545 1/20 0.54
ALDH1A1 P00352 2/20 0.51
HDAC8 Q9BY41 2/20 0.51
TYR P14679 1/20 0.50
ERAP2 Q6P179 1/20 0.49
LNPEP Q9UIQ6 1/20 0.49
CA12 O43570 1/20 0.48
AKR1B10 O60218 1/20 0.48
AKR1B1 P15121 1/20 0.48
CA4 P22748 1/20 0.48
CA6 P23280 1/20 0.48
CA5A P35218 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL630209 1.00 SLC7A5 (0.62) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL16080193 1.00 SLC7A5 (0.62) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL25982889 1.00 SLC7A5 (0.62) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL26023571 1.00 SLC7A5 (0.62) SLC7A5ALPIPKMPTGS1XIAP
Hydrochloric Acid SCHEMBL9831417 0.98 SLC7A5 (0.60) SLC7A5ALPIPKMPTGS1XIAP
Hydrochloric Acid SCHEMBL9831421 0.98 SLC7A5 (0.60) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL8030938 0.95 SLC7A5 (0.57) SLC7A5ALPIPKMPTGS1XIAP
Hydrochloric Acid SCHEMBL8030935 0.94 SLC7A5 (0.55) SLC7A5ALPIPKMPTGS1XIAP
Methoxymethane SCHEMBL9818529 0.94 SLC7A5 (0.55) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL8012238 0.93 SLC7A5 (0.65) SLC7A5SLC15A1LTA4HLAP3HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 412 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4448547-A1 APELINERGIC MACROCYCLES AND USES THEREOF Socpra Sciences Santé Et Humaines S.E.C. (CA) 2024-10-23 EP claimed
US-20240343761-A1 APELINERGIC MACROCYCLES AND USES THEREOF SOCPRA SCIENCES SANTÉ ET HUMAINES S.E.C. (CA) 2024-10-17 US claimed
WO-2023108291-A9 APELINERGIC MACROCYCLES AND USES THEREOF SOCPRA SCIENCES SANTÉ ET HUMAINES S.E.C. (CA) 2023-09-28 WO claimed
CN-110637007-B9 Synthesis of tyrosine-derived diphenol monomers 美敦力公司 2023-08-15 CN claimed
WO-2023108291-A1 APELINERGIC MACROCYCLES AND USES THEREOF SOCPRA SCIENCES SANTÉ ET HUMAINES S.E.C. (CA) 2023-06-22 WO claimed
CN-110637007-B Synthesis of tyrosine-derived diphenol monomers 美敦力公司 2023-06-16 CN claimed
CN-114182537-B Heat-preservation and heat-insulation fabric for outdoor tent and preparation method thereof 仪征龙兴塑胶有限公司 2022-09-16 CN claimed
EP-3634944-B1 SYNTHESIS OF TYROSINE DERIVED DIPHENOL MONOMERS MEDTRONIC INC (US) 2022-06-29 EP claimed
CN-114182537-A Heat-preservation and heat-insulation fabric for outdoor tent and preparation method thereof 仪征龙兴塑胶有限公司 2022-03-15 CN claimed
CN-107556438-B Multi-responsive cross-linked polymer, drug-loaded nano micelle and preparation method thereof 西南民族大学 2020-05-12 CN claimed
CN-1743327-A Indole alkaloid derivative, and its preparing method and use CAPITAL MEDICAL UNIV (CN) 2006-03-08 CN claimed
CN-1202131-C Technology of one kettle method for liquid phase synthesizing thymopentapeptide UNIV JILIN (CN) 2005-05-18 CN claimed
EP-1051195-A4 IDENTIFICATION OF AGENTS THAT PROTECT AGAINST INFLAMMATORY INJURY TO NEURONS BAYLOR COLLEGE MEDICINE (US) 2004-06-09 EP claimed
CN-1442428-A Technology of one kettle method for liquid phase synthesizing thymopentapeptide UNIV JILIN (CN) 2003-09-17 CN claimed
EP-1051195-A1 IDENTIFICATION OF AGENTS THAT PROTECT AGAINST INFLAMMATORY INJURY TO NEURONS BAYLOR COLLEGE OF MEDICINE (US) 2000-11-15 EP claimed
US-6043283-A ADMINISTERING TYRAMINE COMPOUND TO PATIENT TO INHIBIT INJURY, DESTRUCTION OR DEATH OF NEURONS BAYLOR COLLEGE OF MEDICINE (US) 2000-03-28 US claimed
WO-1998011923-A1 IDENTIFICATION OF AGENTS THAT PROTECT AGAINST INFLAMMATORY INJURY TO NEURONS BAYLOR COLLEGE OF MEDICINE (US) 1998-03-26 WO claimed
EP-0527184-B1 PHOSPHORAMIDITE DERIVATIVES, THEIR PREPARATION AND THE USE THEREOF IN THE INCORPORATION OF REPORTER GROUPS ON SYNTHETIC OLIGONUCLEOTIDES AMERSHAM INT PLC (GB) 1995-08-02 EP claimed
EP-0527184-A1 PHOSPHORAMIDITE DERIVATIVES, THEIR PREPARATION AND THE USE THEREOF IN THE INCORPORATION OF REPORTER GROUPS ON SYNTHETIC OLIGONUCLEOTIDES. AMERSHAM INT PLC (GB) 1993-02-17 EP claimed
WO-1991017169-A1 PHOSPHORAMIDITE DERIVATIVES, THEIR PREPARATION AND THE USE THEREOF IN THE INCORPORATION OF REPORTER GROUPS ON SYNTHETIC OLIGONUCLEOTIDES AMERSHAM INTERNATIONAL PLC (GB) 1991-11-14 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240343761-A1 APELINERGIC MACROCYCLES AND USES THEREOF APLNR, AP3D1, AP3B1 SLC7A5 495/4885ALPI 110/4885PKM 2004/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.