Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 7/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | ACP1 | P24666 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | STAT1 | P42224 | 1/20 | 0.57 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6302125 | 0.93 | DYRK1A (0.66) | DYRK1AMAPTKMT2AMEN1ACP1 | |
| SCHEMBL6297226 | 0.89 | KMT2A (0.61) | DYRK1AMAPTKMT2AMEN1ACP1 | |
| SCHEMBL4909104 | 0.87 | CXCR2 (0.76) | DYRK1AMAPTKMT2AMEN1ACP1 | |
| SCHEMBL4908275 | 0.83 | ALDH1A1 (0.71) | DYRK1AMAPTKMT2AMEN1ACP1 | |
| SCHEMBL16732745 | 0.81 | DYRK1A (0.78) | DYRK1AMAPTKMT2AMEN1ACP1 | |
| SCHEMBL2187627 | 0.81 | NPC1 (0.80) | DYRK1AMAPTKMT2AMEN1ACP1 | |
| SCHEMBL6295875 | 0.80 | CXCR2 (0.79) | DYRK1AMAPTKMT2AMEN1ACP1 | |
| SCHEMBL5442278 | 0.78 | NPC1 (0.68) | DYRK1AMAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL31349449 | 0.78 | KMT2A (0.68) | DYRK1AMAPTKMT2AMEN1ACP1 | |
| SCHEMBL31349444 | 0.78 | KMT2A (0.68) | DYRK1AMAPTKMT2AMEN1ACP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6875764-B1 | Urea and thiourea compounds useful for treatment of coccidiosis | NEW PHARMA RESEARCH SWEDEN AB (SE) | 2005-04-05 | — | — | US | disclosed |