Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 5/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.36 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 2/20 | 0.34 |
| ▸ | NAAA | Q02083 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL629274 | 0.79 | PTPN1 (0.60) | BCHEACHEPDE3BPDE3AP2RY12 | |
| SCHEMBL630202 | 0.68 | PTPN1 (0.63) | PTPN1 | |
| SCHEMBL4648799 | 0.68 | PTPN1 (0.38) | PTPN1 | |
| SCHEMBL629366 | 0.67 | PTPN1 (0.59) | PTPN1 | |
| SCHEMBL629293 | 0.67 | PTPN1 (0.58) | PDE3BPDE3AP2RY12PTPN1NAAA | |
| SCHEMBL629760 | 0.66 | PTPN1 (0.57) | PTPN1 | |
| SCHEMBL629812 | 0.66 | PTPN1 (0.60) | PTPN1NAAAHDAC1HDAC8 | |
| SCHEMBL629955 | 0.66 | PTPN1 (0.60) | PTPN1HDAC1 | |
| SCHEMBL629289 | 0.65 | PTPN1 (0.59) | PDE3BPDE3AP2RY12PTPN1NAAA | |
| SCHEMBL629691 | 0.65 | PTPN1 (0.58) | PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1963292-B1 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2012-02-22 | — | — | EP | disclosed |