Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL629366 | 0.83 | PTPN1 (0.59) | PTPN1DDB1CRBN | |
| SCHEMBL4784078 | 0.81 | PTPN1 (0.39) | PTPN1 | |
| SCHEMBL4557317 | 0.79 | PTPN1 (0.39) | PTPN1 | |
| SCHEMBL4455622 | 0.73 | DDB1 (0.31) | DDB1CRBN | |
| SCHEMBL629735 | 0.71 | PTPN1 (0.56) | PTPN1 | |
| SCHEMBL629274 | 0.70 | PTPN1 (0.60) | PTPN1 | |
| SCHEMBL2929513 | 0.69 | PTPN1 (0.41) | PTPN1 | |
| SCHEMBL630220 | 0.68 | BCHE (0.37) | PTPN1 | |
| SCHEMBL14299363 | 0.67 | CYP1A2 (0.53) | — | |
| SCHEMBL629955 | 0.66 | PTPN1 (0.60) | PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1963292-A2 | ORGANIC COMPOUNDS | Novartis Pharma AG (CH) | 2008-09-03 | — | — | EP | disclosed |
| WO-2007067615-A2 | THIADIAZOLE DERIVATIVES AS ANTIDIABETIC AGENTS | NOVARTIS AG (CH) | 2007-06-14 | — | — | WO | disclosed |