⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30473071 | 0.80 | — | — | |
| SCHEMBL20912953 | 0.74 | — | — | |
| SCHEMBL20787073 | 0.69 | — | — | |
| SCHEMBL3505396 | 0.67 | — | — | |
| SCHEMBL3505392 | 0.67 | — | — | |
| SCHEMBL3505395 | 0.65 | — | — | |
| SCHEMBL8352566 | 0.59 | — | — | |
| SCHEMBL29600843 | 0.59 | ALDH1A1 (0.38) | — | |
| SCHEMBL28679176 | 0.59 | — | — | |
| SCHEMBL11118713 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116602950-A | Methods of treating fibrosis | 诺格拉制药有限公司 | 2023-08-18 | — | — | CN | claimed |
| CN-116157133-A | 2',3' -diacetyluridine substituted with acetoacetyl group at 5' position | 维尔斯达医疗公司 | 2023-05-23 | — | — | CN | claimed |
| CN-1223665-A | Process for preparing cellulose acetoacetate alkanoate | EASTMAN CHEM CO (US) | 1999-07-21 | — | — | CN | claimed |
| US-12637436-B2 | Metabotropic glutamate receptor negative allosteric modulators (NAMs) and uses thereof | Sanford Burnham Prebys Medical Discovery Institute (US) | 2026-05-26 | — | — | US | disclosed |
| CN-117836282-A | Thionolactone, synthetic method, use as comonomer and for polymer functionalization and degradation | 法国特种经营公司 | 2024-04-05 | — | — | CN | disclosed |
| CN-116981672-A | Macrocyclic compounds as CFTR modulators | 爱杜西亚药品有限公司 | 2023-10-31 | — | — | CN | disclosed |
| CN-116602950-A | Methods of treating fibrosis | 诺格拉制药有限公司 | 2023-08-18 | — | — | CN | disclosed |
| CN-115197167-B | 1,2, 4-thiadiazolidine-3, 5-dione compound, and preparation method and application thereof | 中国药科大学 | 2023-07-28 | — | — | CN | disclosed |
| CN-116157133-A | 2',3' -diacetyluridine substituted with acetoacetyl group at 5' position | 维尔斯达医疗公司 | 2023-05-23 | — | — | CN | disclosed |
| US-20230113588-A1 | METABOTROPIC GLUTAMATE RECEPTOR NEGATIVE ALLOSTERIC MODULATORS (NAMS) AND USES THEREOF | Sanford Burnham Prebys Medical Discovery Institute | 2023-04-13 | — | — | US | disclosed |
| CN-113164829-B | Use of known and novel cannabinoids | 贝索制药有限责任公司 | 2023-02-21 | — | — | CN | disclosed |
| WO-2010120300-A1 | PROCESS FOR THE PREPARATION OF (3R)-HYDR0XYBUTYL (3R) -HYDROXYBUTYRATE BY ENZYMATIC ENANTIOSELECTIVE REDUCTION EMPLOYING LACTOBACILLUS BREVIS ALCOHOL DEHYDROGENASE | ISIS INNOVATION LIMITED (GB) | 2010-10-21 | — | — | WO | disclosed |
| WO-2009100250-A1 | CHROMENE DERIVATIVES AND USE THEREOF AS HIF HYDROXYLASE ACTIVITY INHIBITORS | FIBROGEN, INC. (US) | 2009-08-13 | — | — | WO | disclosed |
| EP-1773828-A1 | HETEROCYCLE -SUBSTITUTED CYCLIC UREA DERIVATIVES, PREPARATION THEREOF AND PHARMACEUTICAL USE THEREOF AS KINASE INHIBITORS | Aventis Pharma S.A. (FR) | 2007-04-18 | — | — | EP | disclosed |
| EP-1756081-A1 | 1,1'-(1,2-ETHYNEDIYL)BIS-BENZENE DERIVATIVES AS PTP 1-B INHIBITORS | Applied Research Systems ARS Holding N.V. (AN) | 2007-02-28 | — | — | EP | disclosed |
| WO-2006010642-A1 | HETEROCYCLE-SUBSTITUTED CYCLIC UREA DERIVATIVES, PREPARATION THEREOF AND PHARMACEUTICAL USE THEREOF AS KINASE INHIBITORS | AVENTIS PHARMA S.A. (FR) | 2006-02-02 | — | — | WO | disclosed |
| WO-2005097773-A1 | 1,1’-(1,2-ETHYNEDIYL)BIS-BENZENE DERIVATIVES AS PTP 1-B INHIBITORS | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2005-10-20 | — | — | WO | disclosed |
| CN-1223665-A | Process for preparing cellulose acetoacetate alkanoate | EASTMAN CHEM CO (US) | 1999-07-21 | — | — | CN | disclosed |
| US-5731455-A | ALKYL 2-ALKYLACYLACRYLATE CHEMICAL INTERMEDIATE; ANTICHOLESTEROL AGENTS | SHIONOGI & CO., LTD. (JP) | 1998-03-24 | — | — | US | disclosed |
| US-5502216-A | ANTICHOLESTEROL | SHIONOGI & CO., LTD. (JP) | 1996-03-26 | — | — | US | disclosed |