Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ITGB1 | P05556 | 6/20 | 0.47 |
| ▸ | ITGA5 | P08648 | 3/20 | 0.47 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.47 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.47 |
| ▸ | ITGA4 | P13612 | 3/20 | 0.45 |
| ▸ | BDKRB1 | P46663 | 2/20 | 0.41 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.41 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1383043 | 1.00 | LMNA (0.53) | LMNAPOLBKCNQ1KMT2AITGB1 | |
| SCHEMBL13206969 | 1.00 | LMNA (0.53) | LMNAPOLBKCNQ1KMT2AITGB1 | |
| SCHEMBL1382765 | 0.91 | POLB (0.54) | LMNAPOLBKCNQ1KMT2AITGB1 | |
| SCHEMBL630349 | 0.91 | POLB (0.54) | LMNAPOLBKCNQ1KMT2AITGB1 | |
| SCHEMBL631181 | 0.90 | LMNA (0.44) | LMNAPOLBKCNQ1KMT2AHCRTR1 | |
| SCHEMBL13206972 | 0.89 | POLB (0.53) | POLBKCNQ1ITGB1ITGA5HCRTR1 | |
| SCHEMBL8269061 | 0.89 | POLB (0.53) | POLBKCNQ1ITGB1ITGA5HCRTR1 | |
| SCHEMBL630004 | 0.89 | POLB (0.53) | POLBKCNQ1ITGB1ITGA5HCRTR1 | |
| SCHEMBL13206964 | 0.88 | POLB (0.51) | LMNAPOLBKCNQ1KMT2AITGB1 | |
| SCHEMBL1383068 | 0.88 | POLB (0.51) | LMNAPOLBKCNQ1KMT2AITGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778637-B1 | FKBP-binding composition and pharmaceutical use thereof | AVENTIS PHARMA INC (US) | 2012-02-22 | — | — | EP | claimed |
| EP-1778637-B1 | FKBP-binding composition and pharmaceutical use thereof | AVENTIS PHARMA INC (US) | 2012-02-22 | — | — | EP | disclosed |