Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6304648 | 1.00 | TLR4 (0.38) | TLR4 | |
| SCHEMBL12032003 | 0.89 | TLR4 (0.38) | TLR4 | |
| SCHEMBL12031924 | 0.89 | TLR4 (0.38) | TLR4 | |
| SCHEMBL6058639 | 0.88 | TLR4 (0.36) | TLR4 | |
| SCHEMBL9151186 | 0.88 | TLR4 (0.36) | TLR4 | |
| SCHEMBL9151882 | 0.86 | TLR4 (0.35) | TLR4 | |
| SCHEMBL9151877 | 0.86 | TLR4 (0.35) | TLR4 | |
| SCHEMBL9767719 | 0.86 | TLR4 (0.35) | TLR4 | |
| SCHEMBL24325564 | 0.82 | CYP1A2 (0.36) | — | |
| SCHEMBL15684073 | 0.82 | CYP1A2 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6916513-B2 | High dielectric anisotropy and low birefringence; liquid crystal mixtures | MERCK PATENT GMBH (DE) | 2005-07-12 | — | — | US | disclosed |
| US-20040119050-A1 | liquid-crystal display element and an electro-optical display element. | MERCH PATENT GMBH (DE) | 2004-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040119050-A1 | liquid-crystal display element and an electro-optical display element. | CXCR1, DERL1, TTI2 | TLR4 1016/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.