Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PER2 | O15055 | 2/20 | 0.39 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.37 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.32 |
| ▸ | AOC2 | O75106 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28158836 | 0.84 | PRMT5 (0.40) | PER2CRY2PRMT5WDR77POLB | |
| SCHEMBL2704724 | 0.82 | PER2 (0.36) | PER2CRY2PRMT5WDR77POLB | |
| SCHEMBL17393465 | 0.82 | PRMT5 (0.36) | PER2CRY2PRMT5WDR77POLB | |
| SCHEMBL5477108 | 0.81 | GAA (0.40) | PER2CRY2PRMT5WDR77POLB | |
| SCHEMBL771561 | 0.75 | — | — | |
| SCHEMBL8741576 | 0.75 | — | — | |
| SCHEMBL4600250 | 0.75 | — | — | |
| SCHEMBL12495761 | 0.75 | — | — | |
| SCHEMBL1446194 | 0.73 | PRMT5 (0.38) | PER2CRY2PRMT5WDR77POLB | |
| SCHEMBL18920709 | 0.72 | CYP11B1 (0.44) | PRMT5WDR77GAASMN1; SMN2CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102020616-B | Method for preparing 2-(3-oxo-morpholine) acetonitrile | SINOCHEM CORP | 2013-03-27 | — | — | CN | claimed |
| CN-102020616-A | Method for preparing 2-(3-oxo-morpholine) acetonitrile | SINOCHEM CORP | 2011-04-20 | — | — | CN | claimed |
| CN-102020616-B | Method for preparing 2-(3-oxo-morpholine) acetonitrile | SINOCHEM CORP | 2013-03-27 | — | — | CN | disclosed |
| CN-102020616-B | Method for preparing 2-(3-oxo-morpholine) acetonitrile | SINOCHEM CORP | 2013-03-27 | — | — | CN | disclosed |
| CN-102020616-B | Method for preparing 2-(3-oxo-morpholine) acetonitrile | SINOCHEM CORP | 2013-03-27 | — | — | CN | disclosed |
| CN-102020616-A | Method for preparing 2-(3-oxo-morpholine) acetonitrile | SINOCHEM CORP | 2011-04-20 | — | — | CN | disclosed |
| CN-102020616-A | Method for preparing 2-(3-oxo-morpholine) acetonitrile | SINOCHEM CORP | 2011-04-20 | — | — | CN | disclosed |
| CN-102020616-A | Method for preparing 2-(3-oxo-morpholine) acetonitrile | SINOCHEM CORP | 2011-04-20 | — | — | CN | disclosed |
| US-6903089-B1 | Lactam-substituted pyrazolopyridine derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2005-06-07 | — | — | US | disclosed |
| EP-1339716-B1 | LACTAM-SUBSTITUTED PYRAZOLOPYRIDINE DERIVATIVES | BAYER HEALTHCARE AG (DE) | 2004-11-03 | — | — | EP | disclosed |
| EP-1339716-A1 | NOVEL LACTAME-SUBSTITUTED PYRAZOLOPYRIDINE DERIVATIVES | Bayer Aktiengesellschaft (DE) | 2003-09-03 | — | — | EP | disclosed |
| WO-2002042299-A1 | NOVEL LACTAME-SUBSTITUTED PYRAZOLOPYRIDINE DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2002-05-30 | — | — | WO | disclosed |