Known targets — ChEMBL curated mechanism
ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3CHRM1CHRM2CHRM3CHRM4ESR1ESR2GABRA1GABRB1GABRG2GBA1HRH1HTR1DHTR2AOPRD1OPRK1OPRM1SLC6A2SLC6A3TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Cadaverine Tartrate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.35 |
| ▸ | HTR2A known ✓ | P28223 | 1/20 | 0.35 |
| ▸ | ADRA1A known ✓ | P35348 | 1/20 | 0.35 |
| ▸ | HRH1 known ✓ | P35367 | 1/20 | 0.35 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 4/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cadaverine Tartrate SCHEMBL27469398 | 1.00 | TSHR (0.53) | TSHRTP53CYP2C9PDE4ATDP1 | |
| Lactic Acid SCHEMBL27689074 | 0.84 | TP53 (0.58) | TP53TDP1CHRM1AKR1A1CHRM3 | |
| Cadaverine Tartrate SCHEMBL5874760 | 0.81 | TSHR (0.56) | TSHRTP53CYP2C9PDE4ATDP1 | |
| Cadaverine Tartrate SCHEMBL5874765 | 0.81 | TSHR (0.56) | TSHRTP53CYP2C9PDE4ATDP1 | |
| Cadaverine Tartrate SCHEMBL18987140 | 0.80 | TSHR (0.71) | TSHRTP53CYP2C9PDE4ATDP1 | |
| Cadaverine Tartrate SCHEMBL2158124 | 0.77 | TSHR (0.67) | TSHRTP53CYP2C9PDE4ATDP1 | |
| Oxalic Acid SCHEMBL6313261 | 0.77 | FFAR3 (0.39) | TSHRTDP1HDAC1HDAC2LMNA | |
| Acetic Acid SCHEMBL5068220 | 0.77 | FFAR3 (0.47) | TSHRTDP1CHRM1CHRM3HDAC1 | |
| Oxalic Acid SCHEMBL7866905 | 0.77 | FFAR3 (0.39) | TSHRTDP1HDAC1HDAC2LMNA | |
| Cadaverine Tartrate SCHEMBL282045 | 0.77 | TSHR (0.67) | TSHRTP53CYP2C9PDE4ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6841061-B1 | Antigelling agent for hydrocarbon mixture containing conjugated diene and method of preventing clogging of apparatus for separating and purifying the mixture | ZEON CORPORATION (JP) | 2005-01-11 | — | — | US | disclosed |
| CN-1168799-C | Antigelling agent for hydrocarbon mixture containing conjugated and method for preventing clogging of apparatus for separating and purifying mixture | �ձ�������ʽ���� | 2004-09-29 | — | — | CN | disclosed |
| US-6770222-B1 | HYDROXYLAMINES AND PHOSPHORUS CONTAINING COMPOUND | NIPPON ZEON CO., LTD. (JP) | 2004-08-03 | — | — | US | disclosed |
| CN-1355835-A | Antigelling agent for hydrocarbon mixture containing conjugated and method for preventing clogging of apparatus for separating and purifying mixture | NIPPON ZEON CO (JP) | 2002-06-26 | — | — | CN | disclosed |
| EP-1184444-A1 | ANTIGELLING AGENT FOR HYDROCARBON MIXTURE CONTAINING CONJUGATED DIENE AND METHOD OF PREVENTING CLOGGING OF APPARATUS FOR SEPARATING AND PURIFYING THE MIXTURE | Nippon Zeon Co., Ltd. (JP) | 2002-03-06 | — | — | EP | disclosed |
| EP-1061059-A1 | POLYMERIZATION-INHIBITING COMPOSITION, POLYMERIZATION INHIBITOR AND METHOD FOR INHIBITING POLYMERIZATION | NIPPON ZEON CO., LTD. (JP) | 2000-12-20 | — | — | EP | disclosed |