SCHEMBL630675

SCHEMBL630675

Nc1ncnc2c1ncn2C1C=CC(O)C1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
AHCY P23526 12/20 1.00
ADORA2A P29274 1/20 0.55
ADORA3 P0DMS8 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29767847 1.00 AHCY (1.00) AHCYADORA2AADORA3
SCHEMBL12280626 1.00 AHCY (1.00) AHCYADORA2AADORA3
SCHEMBL29374741 1.00 AHCY (1.00) AHCYADORA2AADORA3
SCHEMBL2418669 1.00 AHCY (1.00) AHCYADORA2AADORA3
SCHEMBL10010471 1.00 AHCY (1.00) AHCYADORA2AADORA3
SCHEMBL27003100 0.83 AHCY (0.71) AHCYADORA2AADORA3
SCHEMBL14028190 0.82 AHCY (0.70) AHCYADORA2AADORA3
SCHEMBL4952005 0.82 AHCY (0.70) AHCYADORA2AADORA3
SCHEMBL26804582 0.82 AHCY (0.70) AHCY
SCHEMBL29706988 0.78 AHCY (0.64) AHCY

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3427755-B1 HPV PARTICLES AND USES THEREOF INST NAT SANTE RECH MED (FR) 2020-10-21 EP disclosed
US-10688172-B2 HPV particles and uses thereof INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) 2020-06-23 US disclosed
US-10596275-B2 Virion-derived nanospheres for selective delivery of therapeutic and diagnostic agents to cancer cells AURA BIOSCIENCES, INC. (US) 2020-03-24 US disclosed
US-20190275176-A1 VIRION-DERIVED NANOSPHERES FOR SELECTIVE DELIVERY OF THERAPEUTIC AND DIAGNOSTIC AGENTS TO CANCER CELLS AURA BIOSCIENCES, INC. (US) 2019-09-12 US disclosed
US-10300150-B2 Virion-derived nanospheres for selective delivery of therapeutic and diagnostic agents to cancer cells AURA BIOSCIENCES, INC. (US) 2019-05-28 US disclosed
US-20190142925-A1 HPV PARTICLES AND USES THEREOF INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) 2019-05-16 US disclosed
EP-3427755-A1 HPV PARTICLES AND USES THEREOF INSERM - Institut National de la Santé et de la Recherche Médicale (FR) 2019-01-16 EP disclosed
US-10179168-B2 HPV particles and uses thereof INSERM (Institut National de la Santé et de la Recherche Médicale (FR) 2019-01-15 US disclosed
EP-2419143-B1 HPV PARTICLES AND USES THEREOF INST NAT SANTE RECH MED (FR) 2018-05-09 EP disclosed
US-20180110883-A1 VIRION-DERIVED NANOSPHERES FOR SELECTIVE DELIVERY OF THERAPEUTIC AND DIAGNOSTIC AGENTS TO CANCER CELLS AURA BIOSCIENCES, INC. (US) 2018-04-26 US disclosed
US-20170274099-A1 VIRION-DERIVED NANOSPHERES FOR SELECTIVE DELIVERY OF THERAPEUTIC AND DIAGNOSTIC AGENTS TO CANCER CELLS AURA BIOSCIENCES, INC. (US) 2017-09-28 US disclosed
US-9724404-B2 HPV particles and uses thereof INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) 2017-08-08 US disclosed
US-9700639-B2 Virion-derived nanospheres for selective delivery of therapeutic and diagnostic agents to cancer cells AURA BIOSCIENCES, INC. (US) 2017-07-11 US disclosed
US-20140377170-A1 VIRION-DERIVED NANOSPHERES FOR SELECTIVE DELIVERY OF THERAPEUTIC AND DIAGNOSTIC AGENTS TO CANCER CELLS AURA BIOSCIENCES, INC. (US) 2014-12-25 US disclosed
WO-2013119877-A1 VIRION-DERIVED NANOSPHERES FOR SELECTIVE DELIVERY OF THERAPEUTIC AND DIAGNOSTIC AGENTS TO CANCER CELLS AURA BIOSCIENCES, INC. (US) 2013-08-15 WO disclosed
US-20130012566-A1 Virion Derived Protein Nanoparticles For Delivering Diagnostic Or Therapeutic Agents For The Treatment of Alopecia AURA BIOSCIENCES, INC. (US) 2013-01-10 US disclosed
US-20120171290-A1 HPV PARTICLES AND USES THEREOF AURA BIOSCIENCES, INC. 2012-07-05 US disclosed
EP-2419143-A1 HPV PARTICLES AND USES THEREOF INSERM - Institut National de la Santé et de la Recherche Médicale (FR) 2012-02-22 EP disclosed
WO-2010120266-A1 HPV PARTICLES AND USES THEREOF INSERM, INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) 2010-10-21 WO disclosed
US-4859677-A Nucleoside analogues having antiviral activity UNIVERSITY OF KANSAS (US) 1989-08-22 US disclosed