Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 4/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.39 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 2/20 | 0.37 |
| ▸ | AURKA | O14965 | 2/20 | 0.35 |
| ▸ | DAPK3 | O43293 | 2/20 | 0.35 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.35 |
| ▸ | RET | P07949 | 2/20 | 0.35 |
| ▸ | IGF1R | P08069 | 2/20 | 0.35 |
| ▸ | PIM1 | P11309 | 2/20 | 0.35 |
| ▸ | CLK2 | P49760 | 2/20 | 0.35 |
| ▸ | GSK3A | P49840 | 2/20 | 0.35 |
| ▸ | GSK3B | P49841 | 2/20 | 0.35 |
| ▸ | PRKX | P51817 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6307456 | 0.79 | CSNK2A1 (0.41) | CSNK2A1DYRK1ACSNK2A2MEN1RAB9A | |
| SCHEMBL20200208 | 0.79 | CSNK2A1 (0.41) | CSNK2A1DYRK1ACSNK2A2MEN1RAB9A | |
| SCHEMBL20399971 | 0.79 | CSNK2A1 (0.45) | CSNK2A1DYRK1ACSNK2A2MEN1RAB9A | |
| SCHEMBL31315058 | 0.79 | CSNK2A1 (0.41) | CSNK2A1DYRK1ACSNK2A2MEN1RAB9A | |
| SCHEMBL17253699 | 0.79 | CSNK2A1 (0.41) | CSNK2A1DYRK1ACSNK2A2MEN1RAB9A | |
| SCHEMBL197041 | 0.73 | CSNK2A1 (0.47) | CSNK2A1DYRK1ACSNK2A2MEN1RAB9A | |
| SCHEMBL2906446 | 0.73 | CSNK2A1 (0.47) | CSNK2A1DYRK1ACSNK2A2MEN1RAB9A | |
| SCHEMBL30663427 | 0.73 | CSNK2A1 (0.47) | CSNK2A1DYRK1ACSNK2A2MEN1RAB9A | |
| SCHEMBL31135882 | 0.71 | CSNK2A1 (0.45) | CSNK2A1DYRK1ACSNK2A2MEN1RAB9A | |
| SCHEMBL16475165 | 0.71 | CSNK2A1 (0.45) | CSNK2A1DYRK1ACSNK2A2MEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040116362-A1 | Novel nucleosides and related processes, pharmaceutical compositions and methods | YALE UNIVERSITY | 2004-06-17 | — | — | US | claimed |
| US-6960568-B2 | Nucleosides and related processes, pharmaceutical compositions and methods | YALE UNIVERSITY (US) | 2005-11-01 | — | — | US | disclosed |
| US-20050239726-A1 | Novel nucleosides and related processes, pharmaceutical compositions and methods | YALE UNIVERSITY (US) | 2005-10-27 | — | — | US | disclosed |
| US-20040116362-A1 | Novel nucleosides and related processes, pharmaceutical compositions and methods | YALE UNIVERSITY | 2004-06-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050239726-A1 | Novel nucleosides and related processes, pharmaceutical compositions and methods | ADAR, DCTD, ADA | CSNK2A1 3461/4885DYRK1A 1157/4885CSNK2A2 3725/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.