Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.68 |
| ▸ | NPC1 | O15118 | 5/20 | 0.68 |
| ▸ | RAB9A | P51151 | 5/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.68 |
| ▸ | MAPT | P10636 | 4/20 | 0.68 |
| ▸ | MEN1 | O00255 | 4/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | MGAM | O43451 | 1/20 | 0.49 |
| ▸ | TUBB4A | P04350 | 6/20 | 0.47 |
| ▸ | TUBB | P07437 | 6/20 | 0.47 |
| ▸ | TUBA3C | P0DPH7 | 6/20 | 0.47 |
| ▸ | TUBA1B | P68363 | 6/20 | 0.47 |
| ▸ | TUBA4A | P68366 | 6/20 | 0.47 |
| ▸ | TUBB4B | P68371 | 6/20 | 0.47 |
| ▸ | TUBB3 | Q13509 | 6/20 | 0.47 |
| ▸ | TUBB2A | Q13885 | 6/20 | 0.47 |
| ▸ | TUBB8 | Q3ZCM7 | 6/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6307247 | 1.00 | KDM4E (0.68) | KDM4ENPC1RAB9AKMT2AMAPT | |
| SCHEMBL28465009 | 0.83 | NPC1 (0.68) | KDM4ENPC1RAB9AKMT2AMAPT | |
| SCHEMBL28465286 | 0.81 | KMT2A (1.00) | KDM4ENPC1RAB9AKMT2AMAPT | |
| SCHEMBL29467917 | 0.80 | NPC1 (0.64) | KDM4ENPC1RAB9AKMT2AMAPT | |
| SCHEMBL28258355 | 0.80 | NPC1 (0.64) | KDM4ENPC1RAB9AKMT2AMAPT | |
| SCHEMBL6311013 | 0.76 | NPC1 (0.66) | KDM4ENPC1RAB9AKMT2AMAPT | |
| SCHEMBL6311016 | 0.76 | NPC1 (0.66) | KDM4ENPC1RAB9AKMT2AMAPT | |
| SCHEMBL28899889 | 0.76 | NPC1 (0.52) | KDM4ENPC1RAB9AKMT2AMAPT | |
| SCHEMBL28467881 | 0.74 | FGFR1 (0.50) | KDM4ENPC1RAB9AKMT2AMAPT | |
| SCHEMBL28473184 | 0.72 | NPC1 (0.69) | KDM4ENPC1RAB9AKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6927214-B1 | Non-peptide GLP-1 agonists | NOVO NORDISK A/S (DK) | 2005-08-09 | — | — | US | disclosed |
| EP-1147094-A1 | NON-PEPTIDE GLP-1 AGONISTS | NOVO NORDISK A/S (DK) | 2001-10-24 | — | — | EP | disclosed |
| WO-2000042026-A1 | NON-PEPTIDE GLP-1 AGONISTS | NOVO NORDISK A/S (DK) | 2000-07-20 | — | — | WO | disclosed |