Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 1.00 |
| ▸ | NPC1 | O15118 | 7/20 | 1.00 |
| ▸ | RAB9A | P51151 | 7/20 | 1.00 |
| ▸ | MEN1 | O00255 | 7/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 1.00 |
| ▸ | MAPT | P10636 | 4/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 1.00 |
| ▸ | GAA | P10253 | 1/20 | 0.78 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.78 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.78 |
| ▸ | MGAM | O43451 | 1/20 | 0.70 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.67 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.65 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.65 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | MAPK10 | P53779 | 5/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6936350 | 0.88 | RAB9A (0.78) | KMT2ANPC1RAB9AMEN1KDM4E | |
| SCHEMBL7105109 | 0.88 | RAB9A (0.78) | KMT2ANPC1RAB9AMEN1KDM4E | |
| SCHEMBL1900921 | 0.86 | KMT2A (0.74) | KMT2ANPC1RAB9AMEN1KDM4E | |
| SCHEMBL24701466 | 0.84 | RAB9A (0.72) | KMT2ANPC1RAB9AMEN1KDM4E | |
| SCHEMBL6307248 | 0.81 | KDM4E (0.68) | KMT2ANPC1RAB9AMEN1KDM4E | |
| SCHEMBL28465009 | 0.81 | NPC1 (0.68) | KMT2ANPC1RAB9AMEN1KDM4E | |
| SCHEMBL6307247 | 0.81 | KDM4E (0.68) | KMT2ANPC1RAB9AMEN1KDM4E | |
| SCHEMBL3977907 | 0.80 | KDM4E (0.66) | KMT2ANPC1RAB9AMEN1KDM4E | |
| SCHEMBL29953857 | 0.80 | KDM4E (0.66) | KMT2ANPC1RAB9AMEN1KDM4E | |
| SCHEMBL1900840 | 0.79 | KMT2A (0.68) | KMT2ANPC1RAB9AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111675665-A | Styryl-containing quinoxalinone derivatives and preparation method thereof | 南京大学 | 2020-09-18 | — | — | CN | disclosed |