SCHEMBL630768

SCHEMBL630768

COc1cccc(OC)c1F

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 4/20 0.58
CA2 P00918 4/20 0.58
CA7 P43166 3/20 0.58
CA9 Q16790 3/20 0.58
CA12 O43570 2/20 0.58
CA14 Q9ULX7 2/20 0.58
CA4 P22748 1/20 0.58
ALDH1A1 P00352 3/20 0.52
TDP1 Q9NUW8 2/20 0.52
ADRA2B P18089 1/20 0.52
PTGS1 P23219 1/20 0.52
TP53 P04637 2/20 0.50
MAPK1 P28482 2/20 0.50
KDM4E B2RXH2 1/20 0.50
LMNA P02545 1/20 0.50
CYP3A4 P08684 1/20 0.50
MAPT P10636 1/20 0.50
HPGD P15428 1/20 0.50
ALOX15 P16050 1/20 0.50
ALOX12 P18054 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL196734 0.87 CA1 (0.50) CA1CA2CA7CA9CA12
SCHEMBL29387155 0.87 CA1 (0.50) CA1CA2CA7CA9CA12
SCHEMBL518108 0.86 CA1 (0.44) CA1CA2CA7CA9CA12
SCHEMBL170725 0.85 CA1 (0.48) CA1CA2CA7CA9CA12
SCHEMBL17039548 0.84 KCNK3 (0.44) CA1CA2CA7CA9CA12
SCHEMBL13347755 0.83 CA1 (0.46) CA1CA2CA7CA9CA12
SCHEMBL1728265 0.83 CA12 (0.46) CA1CA2CA7CA9CA12
SCHEMBL2090612 0.83 CA1 (0.46) CA1CA2CA7CA9CA12
SCHEMBL1118854 0.83 CA1 (0.46) CA1CA2CA7CA9CA12
SCHEMBL16368 0.83 TP53 (0.64) CA1CA2CA7CA9CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115894184-B Method for preparing di (2, 6-dimethoxy phenyl) triethylene glycol 黎明化工研究设计院有限责任公司 2024-07-05 CN claimed
CN-115894184-A Method for preparing di (2, 6-dimethoxyphenyl) triethylene glycol 黎明化工研究设计院有限责任公司 2023-04-04 CN claimed
US-20260078141-A1 8-FLUORO-4-ALKYLUMBELLIFERYL ALPHA-D-GLUCOPYRANOSIDE, BIOLOGICAL STERILIZATION INDICATOR INCLUDING THE SAME AND ITS USE IN A METHOD OF DETERMINING EFFICACY OF A STERILIZATION PROCESS SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2026-03-19 US disclosed
EP-4698520-A1 RAF-MEK PROTEIN COMPLEX MODULATORS AND METHODS OF USE THEREOF Gandeeva Therapeutics, Inc. (US) 2026-02-25 EP disclosed
US-12486301-B2 8-fluoro-4-alkylumbelliferyl α-D-glucopyranoside, biological sterilization indicator including the same and its use in a method of determining efficacy of a sterilization process SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2025-12-02 US disclosed
WO-2024220708-A1 RAF-MEK PROTEIN COMPLEX MODULATORS AND METHODS OF USE THEREOF GANDEEVA THERAPEUTICS, INC. (US) 2024-10-24 WO disclosed
US-20240307577-A1 CHLORINATED 4'-ALKYLUMBELLIFERYL ALPHA-D-GLUCOPYRANOSIDE AND METHOD OF ASSESSING EFFICACY OF A STERILIZATION PROCESS INCLUDING THE SAME SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2024-09-19 US disclosed
CN-115894184-B Method for preparing di (2, 6-dimethoxy phenyl) triethylene glycol 黎明化工研究设计院有限责任公司 2024-07-05 CN disclosed
EP-4373830-A1 CHLORINATED 4'-ALKYLUMBELLIFERYL ALPHA-D-GLUCOPYRANOSIDE AND METHOD OF ASSESSING EFFICACY OF A STERILIZATION PROCESS INCLUDING THE SAME Solventum Intellectual Properties Company (US) 2024-05-29 EP disclosed
EP-4034544-B1 8-FLUORO-4-ALKYLUMBELLIFERYL ALPHA-D-GLUCOPYRANOSIDE, BIOLOGICAL STERILIZATION INDICATOR INCLUDING THE SAME AND ITS USE IN A METHOD OF DETERMINING EFFICACY OF A STERILIZATION PROCESS 3M INNOVATIVE PROPERTIES COMPANY (US) 2023-11-15 EP disclosed
CN-115894184-A Method for preparing di (2, 6-dimethoxyphenyl) triethylene glycol 黎明化工研究设计院有限责任公司 2023-04-04 CN disclosed
US-6229055-B1 SYNTHESIS OF FLUORINATED RESORCINOL WHICH IS USEFUL IN THE PREPARATION OF FLUORINATED FLUORESCEIN AND RHODOL DYES SUITABLE FOR USE AS TRACERS, LABELS, OR INTERMEDIATES MOLECULAR PROBES, INC. 2001-05-08 US disclosed
US-6162931-A Fluorinated xanthene derivatives MOLECULAR PROBES, INC. (US) 2000-12-19 US disclosed
EP-1019453-A1 AROMATIC-SUBSTITUTED XANTHENE DYES THE PERKIN-ELMER CORPORATION (US) 2000-07-19 EP disclosed
EP-1013629-A1 Preparation process of fluorine subsituted aromatic compound Mitsui Chemicals, Inc. (JP) 2000-06-28 EP disclosed
US-6008379-A USEFUL AS FLUORESCENT DYES FOR LABELING THE PERKIN-ELMER CORPORATION (US) 1999-12-28 US disclosed
EP-0740359-B1 Non-aqueous electrolyte secondary cell having shuttle agent SONY CORP (JP) 1999-08-04 EP disclosed
WO-1999016832-A1 AROMATIC-SUBSTITUTED XANTHENE DYES THE PERKIN-ELMER CORPORATION (US) 1999-04-08 WO disclosed
CN-1138219-A Non aqueous electroryte secondary cell with shuttle agent SONY CORP (JP) 1996-12-18 CN disclosed
EP-0740359-A1 Non-aqueous electrolyte secondary cell having shuttle agent SONY CORPORATION (JP) 1996-10-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260078141-A1 8-FLUORO-4-ALKYLUMBELLIFERYL ALPHA-D-GLUCOPYRANOSIDE, BIOLOGICAL STERILIZATION INDICATOR INCLUDING THE SAME AND ITS USE IN A METHOD OF DETERMINING EFFICACY OF A STERILIZATION PROCESS ALPG, UNG, UGDH CA1 1263/4885CA2 2668/4885CA7 1049/4885
US-12486301-B2 8-fluoro-4-alkylumbelliferyl α-D-glucopyranoside, biological sterilization indicator including the same and its use in a method of determining efficacy of a sterilization process ALPG, UNG, UGDH CA1 836/4885CA2 2691/4885CA7 850/4885
US-20240307577-A1 CHLORINATED 4'-ALKYLUMBELLIFERYL ALPHA-D-GLUCOPYRANOSIDE AND METHOD OF ASSESSING EFFICACY OF A STERILIZATION PROCESS INCLUDING THE SAME UGGT1, UGT1A7, UGT1A3 CA1 2498/4885CA2 3945/4885CA7 1569/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.