Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.62 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.38 |
| ▸ | CASR | P41180 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TOP2A | P11388 | 1/20 | 0.37 |
| ▸ | MPO | P05164 | 2/20 | 0.37 |
| ▸ | XDH | P47989 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6306872 | 0.91 | MEN1 (0.50) | MEN1KMT2ARXFP1ALDH1A1POLB | |
| SCHEMBL6309405 | 0.89 | MEN1 (0.60) | MEN1KMT2ARXFP1ALDH1A1POLB | |
| SCHEMBL6309370 | 0.85 | ABCC1 (0.50) | MEN1KMT2ARXFP1ALDH1A1ABCC1 | |
| SCHEMBL6314013 | 0.84 | MEN1 (0.62) | MEN1KMT2ARXFP1ALDH1A1ABCC1 | |
| SCHEMBL6306087 | 0.83 | MEN1 (0.61) | MEN1KMT2ARXFP1ALDH1A1ABCC1 | |
| SCHEMBL6315697 | 0.82 | MEN1 (0.63) | MEN1KMT2ARXFP1ALDH1A1ABCC1 | |
| SCHEMBL6308231 | 0.82 | MEN1 (0.60) | MEN1KMT2ARXFP1ALDH1A1POLB | |
| SCHEMBL6309074 | 0.80 | MEN1 (0.48) | MEN1KMT2AALDH1A1POLBEGFR | |
| SCHEMBL7546939 | 0.78 | MEN1 (0.60) | MEN1KMT2ARXFP1ALDH1A1ABCC1 | |
| SCHEMBL6308550 | 0.78 | MEN1 (0.63) | MEN1KMT2ARXFP1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6890930-B1 | Quinazolinones | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 2005-05-10 | — | — | US | disclosed |