Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 14/20 | 0.40 |
| ▸ | CCKAR | P32238 | 2/20 | 0.36 |
| ▸ | CCKBR | P32239 | 2/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6307590 | 0.93 | SCN9A (0.41) | SCN9ACCKARCCKBRTRPA1 | |
| SCHEMBL8131059 | 0.92 | SCN9A (0.37) | SCN9ACCKARCCKBRCA2 | |
| SCHEMBL6304730 | 0.91 | SCN9A (0.41) | SCN9ACCKARCCKBR | |
| SCHEMBL7568374 | 0.90 | SCN9A (0.39) | SCN9ACCKARCCKBRTRPA1CA2 | |
| SCHEMBL4424746 | 0.90 | SCN9A (0.39) | SCN9ACCKARCCKBRTRPA1CA2 | |
| SCHEMBL4418511 | 0.90 | SCN9A (0.39) | SCN9ACCKARCCKBRTRPA1CA2 | |
| SCHEMBL8140471 | 0.86 | CA2 (0.38) | SCN9ACCKARCCKBRCA2 | |
| SCHEMBL6307611 | 0.84 | SCN9A (0.42) | SCN9ACCKARCCKBR | |
| SCHEMBL8132264 | 0.81 | SCN9A (0.40) | SCN9ACCKARCCKBR | |
| SCHEMBL6305882 | 0.81 | PSEN1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6958330-B1 | Polycyclic α-amino-ε-caprolactams and related compounds | ELAN PHARMACEUTICALS, INC. (US) | 2005-10-25 | — | — | US | claimed |
| EP-1042298-A1 | POLYCYCLIC ALPHA-AMINO-EPSILON-CAPROLACTAMS AND RELATED COMPOUNDS | Elan Pharmaceuticals, Inc. (US) | 2000-10-11 | — | — | EP | claimed |
| WO-1999032453-A1 | POLYCYCLIC α-AMINO-⊂-CAPROLACTAMS AND RELATED COMPOUNDS | ELAN PHARMACEUTICALS, INC. (US) | 1999-07-01 | — | — | WO | claimed |
| US-6958330-B1 | Polycyclic α-amino-ε-caprolactams and related compounds | ELAN PHARMACEUTICALS, INC. (US) | 2005-10-25 | — | — | US | disclosed |