SCHEMBL6307997

SCHEMBL6307997

CC(CCCN)c1cccc2ccccc12

nearest known ligand 0.61

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HTR1B P28222 1/20 0.45
ALDH1A1 P00352 2/20 0.44
CYP1A2 P05177 2/20 0.44
CYP2C9 P11712 2/20 0.44
CYP2C19 P33261 2/20 0.44
SLC6A4 P31645 1/20 0.43
AOC3 Q16853 1/20 0.42
CASR P41180 1/20 0.40
METAP2 P50579 1/20 0.40
METAP1 P53582 1/20 0.40
EPHX2 P34913 2/20 0.40
KDM4E B2RXH2 1/20 0.40
CYP3A4 P08684 1/20 0.40
SCN1A P35498 1/20 0.40
SCN2A Q99250 1/20 0.40
HSD17B10 Q99714 1/20 0.40
SCN3A Q9NY46 1/20 0.40
HTR2A P28223 1/20 0.40
HRH1 P35367 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6014505 0.89 ALDH1A1 (0.47) ALDH1A1CYP1A2CYP2C9CYP2C19SLC6A4
SCHEMBL2125548 0.84 ALDH1A1 (0.46) ALDH1A1CYP1A2CYP2C9CYP2C19SLC6A4
SCHEMBL6301621 0.83 ALDH1A1 (0.44) ALDH1A1CYP1A2CYP2C9CYP2C19SLC6A4
SCHEMBL2125164 0.83 KDM4E (0.46) ALDH1A1CYP1A2CYP2C9CYP2C19SLC6A4
SCHEMBL30319491 0.83 KDM4E (0.46) ALDH1A1CYP1A2CYP2C9CYP2C19SLC6A4
SCHEMBL1060489 0.83 ALDH1A1 (0.44) ALDH1A1CYP1A2CYP2C9CYP2C19SLC6A4
SCHEMBL7382719 0.83 ALDH1A1 (0.44) ALDH1A1CYP1A2CYP2C9CYP2C19SLC6A4
SCHEMBL28893602 0.82 HTR2A (0.51) ALDH1A1CYP1A2CYP2C9CYP2C19SLC6A4
SCHEMBL29484444 0.82 HTR2A (0.51) ALDH1A1CYP1A2CYP2C9CYP2C19SLC6A4
SCHEMBL28422249 0.82 HTR2A (0.51) ALDH1A1CYP1A2CYP2C9CYP2C19SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6869950-B1 Benzimidazole derivatives FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2005-03-22 US disclosed
EP-1142880-A1 BENZIMIDAZOLE DERIVATIVES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2001-10-10 EP disclosed