Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | CASR | P41180 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6306087 | 0.92 | MEN1 (0.61) | EGFRLMNAKDM4EHTTL3MBTL1 | |
| SCHEMBL6306022 | 0.88 | EGFR (0.58) | EGFRLMNAKDM4EHTTL3MBTL1 | |
| SCHEMBL6313584 | 0.85 | CASR (0.67) | LMNAALDH1A1SMN1; SMN2CASRMEN1 | |
| SCHEMBL6306872 | 0.84 | MEN1 (0.50) | EGFRLMNAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL6308767 | 0.83 | EGFR (0.61) | EGFRLMNAKDM4EHTTL3MBTL1 | |
| SCHEMBL6306955 | 0.82 | EGFR (0.72) | EGFRLMNAKDM4EHTTL3MBTL1 | |
| SCHEMBL6306848 | 0.81 | KDM4E (0.59) | EGFRLMNAKDM4EHTTL3MBTL1 | |
| SCHEMBL6307827 | 0.81 | EGFR (0.58) | EGFRLMNAKDM4EHTTL3MBTL1 | |
| SCHEMBL6306907 | 0.81 | MEN1 (0.59) | EGFRLMNAKDM4EHTTL3MBTL1 | |
| SCHEMBL6307692 | 0.80 | EGFR (0.69) | EGFRLMNAKDM4EHTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6890930-B1 | Quinazolinones | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 2005-05-10 | — | — | US | disclosed |