Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | RAD52 | P43351 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | CASR | P41180 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6306022 | 0.92 | EGFR (0.58) | MEN1KMT2ATSHRALDH1A1RXFP1 | |
| SCHEMBL6306087 | 0.89 | MEN1 (0.61) | MEN1KMT2AALDH1A1RXFP1EGFR | |
| SCHEMBL6314905 | 0.84 | ALDH1A1 (0.64) | MEN1KMT2ATSHRALDH1A1RXFP1 | |
| SCHEMBL6309405 | 0.83 | MEN1 (0.60) | MEN1KMT2ATSHRALDH1A1RXFP1 | |
| SCHEMBL6308160 | 0.82 | MEN1 (0.59) | MEN1KMT2AALDH1A1RXFP1EGFR | |
| SCHEMBL6314793 | 0.82 | MEN1 (0.61) | MEN1KMT2AALDH1A1RXFP1EGFR | |
| SCHEMBL6308766 | 0.82 | MEN1 (0.61) | MEN1KMT2AALDH1A1RXFP1EGFR | |
| SCHEMBL6308186 | 0.81 | EGFR (0.61) | MEN1KMT2AALDH1A1RXFP1EGFR | |
| SCHEMBL6313159 | 0.81 | MEN1 (0.60) | MEN1KMT2AALDH1A1RXFP1EGFR | |
| SCHEMBL6313824 | 0.78 | MEN1 (0.62) | MEN1KMT2AALDH1A1RXFP1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6890930-B1 | Quinazolinones | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 2005-05-10 | — | — | US | disclosed |