SCHEMBL6308951

SCHEMBL6308951

COC(=O)CCc1ccc(Nc2ccc(-c3ccccc3)cc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 5/20 0.56
FFAR4 Q5NUL3 2/20 0.55
MMP12 P39900 2/20 0.54
PTPN1 P18031 2/20 0.50
EPHX2 P34913 1/20 0.48
HRH3 Q9Y5N1 1/20 0.48
TDP1 Q9NUW8 1/20 0.47
CA12 O43570 1/20 0.47
CA7 P43166 1/20 0.47
CA9 Q16790 1/20 0.47
CA14 Q9ULX7 1/20 0.47
HDAC2 Q92769 1/20 0.47
MEN1 O00255 1/20 0.46
ALDH1A1 P00352 1/20 0.46
GAA P10253 1/20 0.46
MAPT P10636 1/20 0.46
KMT2A Q03164 1/20 0.46
LTB4R Q15722 1/20 0.46
IDO1 P14902 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2776004 0.92 TDP1 (0.51) FFAR1FFAR4PTPN1EPHX2TDP1
SCHEMBL480043 0.92 FFAR1 (0.65) FFAR1FFAR4MMP12PTPN1HRH3
SCHEMBL4827768 0.92 FFAR1 (0.65) FFAR1FFAR4MMP12PTPN1HRH3
SCHEMBL14683408 0.90 SIRT2 (0.52) FFAR1FFAR4MMP12PTPN1EPHX2
SCHEMBL14717782 0.89 EPHX2 (0.56) FFAR1EPHX2HRH3ALDH1A1MAPT
SCHEMBL6313869 0.88 SIRT2 (0.47) FFAR1FFAR4MMP12PTPN1HRH3
SCHEMBL12431333 0.88 EPHX2 (0.48) FFAR1FFAR4EPHX2HRH3GAA
Methyl 3-Phenylpropanoate SCHEMBL9424369 0.87 TDP1 (0.61) FFAR1MMP12HRH3TDP1CA12
SCHEMBL6308956 0.85 SIRT2 (0.49) FFAR1FFAR4PTPN1TDP1CA12
SCHEMBL12646541 0.84 PTPN1 (0.55) FFAR1FFAR4MMP12PTPN1HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9188885-B2 Reactive compound, charge transporting film, photoelectric conversion device, electrophotographic photoreceptor and method of producing the same, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2015-11-17 US disclosed
US-9188885-B2 Reactive compound, charge transporting film, photoelectric conversion device, electrophotographic photoreceptor and method of producing the same, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2015-11-17 US disclosed
US-9188885-B2 Reactive compound, charge transporting film, photoelectric conversion device, electrophotographic photoreceptor and method of producing the same, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2015-11-17 US disclosed
US-20140079435-A1 NOVEL REACTIVE COMPOUND, CHARGE TRANSPORTING FILM, PHOTOELECTRIC CONVERSION DEVICE, ELECTROPHOTOGRAPHIC PHOTORECEPTOR AND METHOD OF PRODUCING THE SAME, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2014-03-20 US disclosed
US-20140079435-A1 NOVEL REACTIVE COMPOUND, CHARGE TRANSPORTING FILM, PHOTOELECTRIC CONVERSION DEVICE, ELECTROPHOTOGRAPHIC PHOTORECEPTOR AND METHOD OF PRODUCING THE SAME, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2014-03-20 US disclosed
US-20140079435-A1 NOVEL REACTIVE COMPOUND, CHARGE TRANSPORTING FILM, PHOTOELECTRIC CONVERSION DEVICE, ELECTROPHOTOGRAPHIC PHOTORECEPTOR AND METHOD OF PRODUCING THE SAME, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2014-03-20 US disclosed
US-8669029-B2 Reactive compound, charge transporting film, photoelectric conversion device, electrophotographic photoreceptor and method of producing the same, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2014-03-11 US disclosed
US-8669029-B2 Reactive compound, charge transporting film, photoelectric conversion device, electrophotographic photoreceptor and method of producing the same, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2014-03-11 US disclosed
US-8669029-B2 Reactive compound, charge transporting film, photoelectric conversion device, electrophotographic photoreceptor and method of producing the same, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2014-03-11 US disclosed
US-20130052573-A1 NOVEL REACTIVE COMPOUND, CHARGE TRANSPORTING FILM, PHOTOELECTRIC CONVERSION DEVICE, ELECTROPHOTOGRAPHIC PHOTORECEPTOR AND METHOD OF PRODUCING THE SAME, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2013-02-28 US disclosed
US-20090243469-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND DISPLAY DEVICE INCLUDING THE SAME FUJI XEROX CO., LTD. (JP) 2009-10-01 US disclosed
US-20090243469-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND DISPLAY DEVICE INCLUDING THE SAME FUJI XEROX CO., LTD. (JP) 2009-10-01 US disclosed
US-20090039774-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND DISPLAY DEVICE FUJI XEROX CO., LTD. (JP) 2009-02-12 US disclosed
US-20090039774-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND DISPLAY DEVICE FUJI XEROX CO., LTD. (JP) 2009-02-12 US disclosed
US-20080306239-A1 QUINOXALINE-CONTAINING COMPOUNDS AND POLYMERS THEREOF FUJI XEROX CO., LTD. (JP) 2008-12-11 US disclosed
US-20080306239-A1 QUINOXALINE-CONTAINING COMPOUNDS AND POLYMERS THEREOF FUJI XEROX CO., LTD. (JP) 2008-12-11 US disclosed
CN-100334128-C Charge transfer polymer FUJI XERON CO LTD (JP) 2007-08-29 CN disclosed
US-6936679-B2 Charge-transporting polymer FUJI XEROX CO., LTD. (JP) 2005-08-30 US disclosed
US-20030207187-A1 Charge-transporting polymer FUJI XEROX CO., LTD. (JP) 2003-11-06 US disclosed
CN-1445258-A Charge transfer polymer FUJI XERON CO LTD (JP) 2003-10-01 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080306239-A1 QUINOXALINE-CONTAINING COMPOUNDS AND POLYMERS THEREOF ARL1, NMRAL1, PDXK FFAR1 3169/4885FFAR4 4519/4885MMP12 4845/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.