SCHEMBL6308966

SCHEMBL6308966

CN(C)c1ccc2c(c1)Sc1cc(N(C)C)cc(C(N)=O)c1N2CC(=O)O

nearest known ligand 0.46

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ MAPK1 P28482 2/20 0.46
▸ MEN1 O00255 2/20 0.46
▸ KMT2A Q03164 2/20 0.46
▸ TDP1 Q9NUW8 1/20 0.46
▸ L3MBTL1 Q9Y468 1/20 0.46
▸ SNCA P37840 1/20 0.38
▸ KDM4E B2RXH2 2/20 0.33
▸ TP53 P04637 1/20 0.33
▸ BCHE P06276 1/20 0.32
▸ P2RX4 Q99571 1/20 0.32
▸ LMNA P02545 1/20 0.31
▸ ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30480968 1.00 MAPK1 (0.46) MAPK1MEN1KMT2ATDP1L3MBTL1
SCHEMBL30595091 0.84 MAPK1 (0.58) MAPK1MEN1KMT2ATDP1L3MBTL1
SCHEMBL6427654 0.82 SNCA (0.50) MAPK1MEN1KMT2ATDP1L3MBTL1
SCHEMBL30480967 0.82 SNCA (0.50) MAPK1MEN1KMT2ATDP1L3MBTL1
SCHEMBL24860289 0.70 MAPK1 (0.65) MAPK1MEN1KMT2ATDP1L3MBTL1
SCHEMBL29378413 0.70 MAPK1 (0.65) MAPK1MEN1KMT2ATDP1L3MBTL1
SCHEMBL1208061 0.69 MAPK1 (0.67) MAPK1MEN1KMT2ATDP1L3MBTL1
SCHEMBL29557693 0.69 MAPK1 (0.67) MAPK1MEN1KMT2ATDP1L3MBTL1
SCHEMBL19404346 0.68 SNCA (0.53) MAPK1MEN1KMT2ATDP1L3MBTL1
SCHEMBL14324570 0.67 HTT (0.35) MEN1KMT2AL3MBTL1TP53LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12049566-B2 Method for preserving leuco chromogen-containing aqueous solution HITACHI CHEMICAL DIAGNOSTICS SYSTEMS CO., LTD. (JP) 2024-07-30 — — US disclosed
US-20190177548-A1 METHOD FOR PRESERVING LEUCO CHROMOGEN-CONTAINING AQUEOUS SOLUTION CANON MEDICAL DIAGNOSTICS CORPORATION (JP) 2019-06-13 — — US disclosed
EP-3492529-A1 METHOD FOR PRESERVING LEUCO CHROMOGEN-CONTAINING AQUEOUS SOLUTION Kyowa Medex Co., Ltd. (JP) 2019-06-05 — — EP disclosed
US-6936473-B2 For separating collected blood into blood cell and blood plasma, right on the spot of collection; for preparing sample for quantification used for clinical diagnosis LEISURE, INC. (JP) 2005-08-30 — — US disclosed
US-20040141888-A1 For separating collected blood into blood cell and blood plasma, right on the spot of collection; efficiency, simplification LEISURE, INC. (JP) 2004-07-22 — — US disclosed
US-20020153316-A1 For separating collected blood into blood cell and blood plasma, right on the spot of collection; for preparing sample for quantification used for clinical diagnosis LEISURE, INC. (JP) 2002-10-24 — — US disclosed
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