Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | CISD2 | Q8N5K1 | 1/20 | 0.31 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.31 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17484559 | 0.69 | MEN1 (0.62) | HTTHSD17B10MEN1KMT2ALMNA | |
| SCHEMBL6308966 | 0.67 | MAPK1 (0.46) | MEN1KMT2ALMNAL3MBTL1TP53 | |
| SCHEMBL30480968 | 0.67 | MAPK1 (0.46) | MEN1KMT2ALMNAL3MBTL1TP53 | |
| SCHEMBL17356849 | 0.64 | ALDH1A1 (0.59) | HTTHSD17B10SMN1; SMN2MEN1KMT2A | |
| SCHEMBL1926809 | 0.63 | NOX1 (0.44) | HSD17B10ALOX15SMN1; SMN2MEN1KMT2A | |
| SCHEMBL1828807 | 0.63 | BCHE (0.37) | KMT2AGAAMAPT | |
| SCHEMBL17482013 | 0.63 | MEN1 (0.54) | HSD17B10SMN1; SMN2MEN1KMT2AGAA | |
| SCHEMBL13212473 | 0.63 | MAPT (0.48) | HTTSMN1; SMN2MEN1KMT2AGAA | |
| SCHEMBL30595091 | 0.62 | MAPK1 (0.58) | MEN1KMT2AGAALMNAL3MBTL1 | |
| SCHEMBL17356858 | 0.60 | MAPT (0.51) | HTTTSHRHSD17B10ALOX15MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8999124-B2 | Detection device | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2015-04-07 | — | — | US | disclosed |
| EP-2543981-A1 | DETECTION DEVICE | Nippon Kayaku Kabushiki Kaisha (JP) | 2013-01-09 | — | — | EP | disclosed |
| US-20120325658-A1 | DETECTION DEVICE | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2012-12-27 | — | — | US | disclosed |