Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6303037 | 0.96 | PARP1 (0.36) | — | |
| SCHEMBL6302669 | 0.94 | PARP1 (0.32) | HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL6304845 | 0.91 | PARP1 (0.39) | HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL6306015 | 0.85 | PARP1 (0.42) | HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL7704907 | 0.84 | HSD17B10 (0.38) | HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL7704945 | 0.84 | HDAC3 (0.44) | HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL7704932 | 0.83 | HDAC3 (0.35) | HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL6309617 | 0.83 | HDAC1 (0.43) | HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL7708363 | 0.83 | TP53 (0.35) | HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL7711422 | 0.83 | HSD17B10 (0.36) | HDAC3HDAC1HDAC2NCOR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6841550-B1 | Benzoxazine and benzothiazine derivatives and their use in medicines | SCHERING AKTIENGESELLSCHAFT (DE) | 2005-01-11 | — | — | US | disclosed |