Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL394437 | 0.91 | TSHR (0.52) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL5701336 | 0.84 | TSHR (0.45) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL1125587 | 0.84 | TSHR (0.55) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL5701744 | 0.82 | TSHR (0.43) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL397195 | 0.81 | TSHR (0.46) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL21066770 | 0.80 | TSHR (0.58) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL26918870 | 0.78 | TSHR (0.61) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL21101831 | 0.78 | TSHR (0.61) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL21108491 | 0.78 | TSHR (0.61) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL9229975 | 0.78 | TSHR (0.56) | TSHRALDH1A1CYP3A4HPGDTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6866764-B2 | Processes for fabricating printed wiring boards using dendritic polymer copper nanocomposite coatings | MICHIGAN MOLECULAR INSTITUTE (US) | 2005-03-15 | — | — | US | claimed |
| EP-0882755-B1 | Radially layered copoly (amidoamineorganosilicon) dendrimers | MICHIGAN MOLECULAR INST (US) | 2002-08-14 | — | — | EP | claimed |
| EP-0928813-A1 | Dendrimer-based nanoscopic sponges and metal composites | DOW CORNING CORPORATION (US) | 1999-07-14 | — | — | EP | claimed |
| EP-0882755-A1 | Radially layered copoly (amidoamineorganosilicon) dendrimers | DOW CORNING CORPORATION (US) | 1998-12-09 | — | — | EP | claimed |
| US-5739218-A | HYDROPHOBIC; WATER INSOLUBILITY; MONOLAYERS ON WATER SUSTAIN SURFACE PRESSURE | DOW CORNING CORPORATION (US) | 1998-04-14 | — | — | US | claimed |
| EP-0893482-B1 | Dendrimer-based networks having lyophilic organosilicon and hydrophilic polyamidoamine nanoscopic domains | MICHIGAN MOLECULAR INST (US) | 2004-05-12 | — | — | EP | disclosed |
| EP-0882755-B1 | Radially layered copoly (amidoamineorganosilicon) dendrimers | MICHIGAN MOLECULAR INST (US) | 2002-08-14 | — | — | EP | disclosed |
| EP-1036809-A1 | High generation radially layered dendrimers | DOW CORNING CORPORATION (US) | 2000-09-20 | — | — | EP | disclosed |
| US-6077500-A | High generation radially layered dendrimers | DOW CORNING CORPORATION (US) | 2000-06-20 | — | — | US | disclosed |
| EP-0928813-A1 | Dendrimer-based nanoscopic sponges and metal composites | DOW CORNING CORPORATION (US) | 1999-07-14 | — | — | EP | disclosed |
| US-5902863-A | HAVING HYDROPHILIC AND HYDROPHOBIC DOMAINS; CONTROLLED SIZE, SHAPE AND DISTRIBUTION; THIN FILMS HAVING OPTICAL CLARITY, TRANSPARENT, COLORLESS AND A NON-STICK SURFACE | DOW CORNING CORPORATION (US) | 1999-05-11 | — | — | US | disclosed |
| EP-0893482-A1 | Dendrimer-based networks having lyophilic organosilicon and hydrophilic polyamidoamine nanoscopic domains | DOW CORNING CORPORATION (US) | 1999-01-27 | — | — | EP | disclosed |
| EP-0882755-A1 | Radially layered copoly (amidoamineorganosilicon) dendrimers | DOW CORNING CORPORATION (US) | 1998-12-09 | — | — | EP | disclosed |
| EP-0882755-A1 | Radially layered copoly (amidoamineorganosilicon) dendrimers | DOW CORNING CORPORATION (US) | 1998-12-09 | — | — | EP | disclosed |
| US-5739218-A | HYDROPHOBIC; WATER INSOLUBILITY; MONOLAYERS ON WATER SUSTAIN SURFACE PRESSURE | DOW CORNING CORPORATION (US) | 1998-04-14 | — | — | US | disclosed |
| US-5739218-A | HYDROPHOBIC; WATER INSOLUBILITY; MONOLAYERS ON WATER SUSTAIN SURFACE PRESSURE | DOW CORNING CORPORATION (US) | 1998-04-14 | — | — | US | disclosed |