SCHEMBL1125587

SCHEMBL1125587

C=CC(=O)OCCCC([SiH3])(OC)OC

nearest known ligand 0.55

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.55
ALDH1A1 P00352 4/20 0.55
CYP3A4 P08684 2/20 0.55
HPGD P15428 1/20 0.55
TP53 P04637 3/20 0.46
HIF1A Q16665 3/20 0.46
HSD17B10 Q99714 1/20 0.46
THRB P10828 2/20 0.42
MAPK1 P28482 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
ATM Q13315 1/20 0.36
HCAR2 Q8TDS4 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21066770 0.95 TSHR (0.58) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL21101831 0.93 TSHR (0.61) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL21108491 0.93 TSHR (0.61) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL26918870 0.93 TSHR (0.61) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL733858 0.89 TSHR (0.48) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL5079805 0.89 TSHR (0.44) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL394437 0.87 TSHR (0.52) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL6309352 0.84 TSHR (0.49) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL4360498 0.84 TSHR (0.49) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL9229975 0.83 TSHR (0.56) TSHRALDH1A1CYP3A4HPGDTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 155 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7615594-B2 Graft copolymers and impact-resistant flame-retardant resin compositions containing the same KANEKA CORPORATION (JP) 2009-11-10 US claimed
US-6841694-B2 Process for stabilizing unsaturated organosilicon compounds WACKER-CHEMIE GMBH (DE) 2005-01-11 US claimed
US-20040171859-A1 Process for stabilizing unsaturated organosilicon compounds WACKER-CHEMIE GMBH (DE) 2004-09-02 US claimed
US-6281297-B1 CONTAINING ALLYL METHACRYLATE AND ORGANOSILICON COMPOUND KANEKA CORPORATION (JP) 2001-08-28 US claimed
WO-2025095375-A1 METHOD FOR PREPARING NON-FLUORINE-BASED SILOXANE-POLYMER COMPOSITE BINDER, NON-FLUORINE-BASED SILOXANE-POLYMER COMPOSITE BINDER PREPARED USING SAME, AND ELECTRODE COMPRISING SAME 한국전기연구원 2025-05-08 WO disclosed
EP-3608292-B1 SILICA PARTICLES NIPPON CATALYTIC CHEM IND (JP) 2024-11-27 EP disclosed
EP-3543246-B1 COMPOSITION CONTAINING ORGANIC SILICON COMPOUND AND PAINT AND ADHESIVE CONTAINING SAID COMPOSITION SHINETSU CHEMICAL CO (JP) 2024-05-15 EP disclosed
EP-4289618-A1 UNDERCOAT AGENT COMPOSITION FOR INORGANIC SUBSTANCE LAYER LAMINATION, CURED PRODUCT THEREOF, AND METHOD FOR PRODUCING SAME Toagosei Co., Ltd. (JP) 2023-12-13 EP disclosed
WO-2023106317-A1 WATER-BASED COATING 株式会社カネカ 2023-06-15 WO disclosed
CN-111095566-B Field effect transistor, method of manufacturing the same, wireless communication device using the same, and merchandise tag 东丽株式会社 2023-05-23 CN disclosed
EP-3514822-B1 METHOD FOR MANUFACTURING FIELD EFFECT TRANSISTOR AND METHOD FOR MANUFACTURING WIRELESS COMMUNICATION DEVICE TORAY INDUSTRIES (JP) 2023-04-26 EP disclosed
CN-111533854-B Silicon modified acrylic resin and application thereof 上海亿祺化工技术有限公司 2023-03-31 CN disclosed
EP-0834535-A1 Thermoplastic resin composition Kaneka Corporation (JP) 1998-04-08 EP disclosed
EP-0806440-A2 Composite rubber particles and graft copolymer particles of composite rubber Kaneka Corporation (JP) 1997-11-12 EP disclosed
US-5658988-A ONE-PACKAGE; AUTOMOBILE FINISHES KANSAI PAINT CO., LTD. (JP) 1997-08-19 US disclosed
US-4684697-A Compositions based on silane hydrolyzates and vinyl polymers containing hydrolyzable silyl groups PPG INDUSTRIES, INC. (US) 1987-08-04 US disclosed
US-4652610-A FLEXIBLE COATINGS; AUTOMOBILE PAINTS PPG INDUSTRIES, INC. (US) 1987-03-24 US disclosed
EP-0212350-A2 Silicon-containing addition interpolymers from isobornyl (meth)acrylate and coating method PPG INDUSTRIES, INC. (US) 1987-03-04 EP disclosed
US-4614777-A Addition interpolymers from isobornyl (meth)acrylate which contain alkoxysilane and/or acyloxysilane groups PPG INDUSTRIES, INC. (US) 1986-09-30 US disclosed
US-4603064-A Color plus clear coating method utilizing addition interpolymers from isobornyl (meth)acrylate which contain alkoxysilane and/or acyloxysilane groups PPG INDUSTRIES, INC. (US) 1986-07-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040171859-A1 Process for stabilizing unsaturated organosilicon compounds ELOVL1, ELOVL6, DEGS1 TSHR 4650/4885ALDH1A1 402/4885CYP3A4 3126/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.